About: Fosfestrol

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Fosfestrol, sold under the brand name Honvan and also known as diethylstilbestrol diphosphate (DESDP), is an estrogen medication which is used in the treatment of prostate cancer in men. It is given by slow intravenous infusion once per day to once per week or by mouth once per day. Fosfestrol was patented in 1941 and was introduced for medical use in 1955. It was previously marketed widely throughout the world, but now remains available in only a few countries.

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dbo:abstract
  • Fosfestrol, sold under the brand name Honvan and also known as diethylstilbestrol diphosphate (DESDP), is an estrogen medication which is used in the treatment of prostate cancer in men. It is given by slow intravenous infusion once per day to once per week or by mouth once per day. Side effects of fosfestrol include nausea and vomiting, cardiovascular complications, blood clots, edema, and genital skin reactions, among others. Fosfestrol is an estrogen, and hence is an agonist of the estrogen receptor, the biological target of estrogens like estradiol. It acts as a prodrug of diethylstilbestrol. Fosfestrol was patented in 1941 and was introduced for medical use in 1955. It was previously marketed widely throughout the world, but now remains available in only a few countries. (en)
  • Фосфэстрол (МНН) (фирменные наименования Хонван, Дифостилбен, Фосфостилбен, Фостролин, Стилбол, Стилфострол, Вагестрол) также известный как диэтилстильбэстрол дифосфат (DESDP, ДЭСП"), является синтетическим лекарством на базе не стероидных эстрогенов из стильбестроловой группы, который используется в лечении рака простаты. Это пролекарство на основе диэтилстильбэстрола. (ru)
dbo:alternativeName
  • Honvan, others (en)
dbo:casNumber
  • 4719-75-9 (tetrasodium)
  • 522-40-7
dbo:chEMBL
  • 1200598
dbo:class
dbo:fdaUniiCode
  • A0E0NMA80F
dbo:kegg
  • D00946
dbo:pubchem
  • 3032325
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  • 20504 (xsd:nonNegativeInteger)
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  • L02 (en)
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  • AA04 (en)
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  • 18 (xsd:integer)
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  • 522 (xsd:integer)
dbp:casSupplemental
  • 4719 (xsd:integer)
dbp:chembl
  • 1200598 (xsd:integer)
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  • 2297327 (xsd:integer)
dbp:class
dbp:h
  • 22 (xsd:integer)
dbp:iupacName
  • [4-[4-hex-3-en-3-yl]phenoxy]phosphonic acid (en)
dbp:kegg
  • D00946 (en)
dbp:legalStatus
  • Rx-only (en)
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  • 8 (xsd:integer)
dbp:p
  • 2 (xsd:integer)
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  • 3032325 (xsd:integer)
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  • O=PO (en)
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  • 1 (xsd:integer)
dbp:stdinchikey
  • NLORYLAYLIXTID-ISLYRVAYSA-N (en)
dbp:synonyms
  • Diethylstilbestrol diphosphate; Stilbestrol diphosphate; DESDP; DESP; DES-DP; DES-P (en)
dbp:tradename
  • Honvan, others (en)
dbp:unii
  • A0E0NMA80F (en)
dbp:verifiedfields
  • verified (en)
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  • 461113468 (xsd:integer)
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rdfs:comment
  • Фосфэстрол (МНН) (фирменные наименования Хонван, Дифостилбен, Фосфостилбен, Фостролин, Стилбол, Стилфострол, Вагестрол) также известный как диэтилстильбэстрол дифосфат (DESDP, ДЭСП"), является синтетическим лекарством на базе не стероидных эстрогенов из стильбестроловой группы, который используется в лечении рака простаты. Это пролекарство на основе диэтилстильбэстрола. (ru)
  • Fosfestrol, sold under the brand name Honvan and also known as diethylstilbestrol diphosphate (DESDP), is an estrogen medication which is used in the treatment of prostate cancer in men. It is given by slow intravenous infusion once per day to once per week or by mouth once per day. Fosfestrol was patented in 1941 and was introduced for medical use in 1955. It was previously marketed widely throughout the world, but now remains available in only a few countries. (en)
rdfs:label
  • Fosfestrol (en)
  • Фосфестрол (ru)
rdfs:seeAlso
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