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The fences and pickets model of plasma membrane is a concept of cell membrane structure suggesting that the fluid plasma membrane is compartmentalized by actin-basedmembrane-skeleton “fences” and anchored transmembrane protein “pickets”. This model differs from older cell membrane structure concepts such as the Singer-Nicolson fluid mosaic modelf and the Saffman-Delbrück two-dimensional continuum fluid model that view the membrane as more or less homogeneous. The fences and pickets model was proposed to explain observations of molecular traffic made due to recent advances in single molecule tracking techniques.

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  • Fences and pickets model složení plazmatické membrány (model plotů a proteinových hlídek) je koncepce popisující složení a dynamiku buněčné membrány. Tento model je založen na představě o rozdělení celého prostoru cytoplazmatické membrány na malé (70-300 nm) prostory, které vznikají jednak kvůli dočasnému propojení buněčné membrány a prvků aktinového cytoskeletu („fences“), a jednak kvůli existenci skupin imobilizovaných transmembránových proteinů, tzv. proteinových „hlídek“ („pickets“), které omezují volný pohyb látek membránovou plochou. Fences and pickets koncepce složení plazmatické membrány postupně nahrazuje starší představy o složení buněčné membrány, jako např., Singerův-Nicolsonův a Saffmanův-Delbruckův . (cs)
  • The fences and pickets model of plasma membrane is a concept of cell membrane structure suggesting that the fluid plasma membrane is compartmentalized by actin-basedmembrane-skeleton “fences” and anchored transmembrane protein “pickets”. This model differs from older cell membrane structure concepts such as the Singer-Nicolson fluid mosaic modelf and the Saffman-Delbrück two-dimensional continuum fluid model that view the membrane as more or less homogeneous. The fences and pickets model was proposed to explain observations of molecular traffic made due to recent advances in single molecule tracking techniques. (en)
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  • The fences and pickets model of plasma membrane is a concept of cell membrane structure suggesting that the fluid plasma membrane is compartmentalized by actin-basedmembrane-skeleton “fences” and anchored transmembrane protein “pickets”. This model differs from older cell membrane structure concepts such as the Singer-Nicolson fluid mosaic modelf and the Saffman-Delbrück two-dimensional continuum fluid model that view the membrane as more or less homogeneous. The fences and pickets model was proposed to explain observations of molecular traffic made due to recent advances in single molecule tracking techniques. (en)
  • Fences and pickets model složení plazmatické membrány (model plotů a proteinových hlídek) je koncepce popisující složení a dynamiku buněčné membrány. Tento model je založen na představě o rozdělení celého prostoru cytoplazmatické membrány na malé (70-300 nm) prostory, které vznikají jednak kvůli dočasnému propojení buněčné membrány a prvků aktinového cytoskeletu („fences“), a jednak kvůli existenci skupin imobilizovaných transmembránových proteinů, tzv. proteinových „hlídek“ („pickets“), které omezují volný pohyb látek membránovou plochou. (cs)
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  • Fences and pickets (cs)
  • Fences and pickets model of plasma membrane structure (en)
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