About: FG-8205

Property	Value
dbo:abstract	FG-8205 (L-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at GABAA receptors, with slight selectivity for the α1-containing subtype. In animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced. (en) L'FG-8205 è uno psicofarmaco appartenente alla categoria delle ed è un analogo del bretazenil; esso agisce come un agonista parziale dei recettori GABA A, con leggera selettività per il sottotipo α1. Nei test sugli animali ha effetti ansiolitici e anticonvulsivanti ma con poca sedazione o atassia prodotta. (it)
dbo:casNumber	122384-14-9
dbo:chEMBL	307202
dbo:fdaUniiCode	7V0I080855
dbo:pubchem	129710
dbo:thumbnail	wiki-commons:Special:FilePath/FG-8205.svg?width=300
dbo:wikiPageID	32813641 (xsd:integer)
dbo:wikiPageLength	3821 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1120043607 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Partial_agonist dbr:Benzodiazepine dbr:Bretazenil dbr:Anticonvulsant dbc:GABAA_receptor_positive_allosteric_modulators dbc:Isopropyl_compounds dbc:Oxadiazoles dbr:Anxiolytic dbc:Imidazobenzodiazepines
dbp:c	17 (xsd:integer)
dbp:casNumber	122384 (xsd:integer)
dbp:chembl	307202 (xsd:integer)
dbp:chemspiderid	114837 (xsd:integer)
dbp:cl	1 (xsd:integer)
dbp:h	16 (xsd:integer)
dbp:iupacName	7 (xsd:integer)
dbp:n	5 (xsd:integer)
dbp:o	2 (xsd:integer)
dbp:pubchem	129710 (xsd:integer)
dbp:smiles	Clc4cccc3n2cncc2CNC (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	SEWXZWMBVGJJPG-UHFFFAOYSA-N (en)
dbp:unii	7 (xsd:integer)
dbp:verifiedfields	changed (en)
dbp:verifiedrevid	461098708 (xsd:integer)
dbp:watchedfields	changed (en)
dbp:width	200 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:GABAAR_PAMs dbt:Nervous-system-drug-stub dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Drugbankcite dbt:Ebicite dbt:Fdacite dbt:Stdinchicite dbt:Benzodiazepines
dcterms:subject	dbc:GABAA_receptor_positive_allosteric_modulators dbc:Isopropyl_compounds dbc:Oxadiazoles dbc:Imidazobenzodiazepines
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatBenzodiazepines yago:Agent114778436 yago:Benzodiazepine102830852 yago:CausalAgent100007347 yago:Drug103247620 yago:DrugOfAbuse103248958 yago:Matter100020827 yago:Medicine103740161 yago:MinorTranquilizer103771443 yago:MuscleRelaxant103800001 yago:PhysicalEntity100001930 yago:PsychotropicAgent104017429 yago:Relaxant104072811 dbo:Drug yago:Sedative-hypnotic104166841 yago:Sedative104166553 yago:Substance100020090 yago:Tranquilizer104470232
rdfs:comment	FG-8205 (L-663,581) is an imidazobenzodiazepine derivative related to bretazenil, which acts as a partial agonist at GABAA receptors, with slight selectivity for the α1-containing subtype. In animal tests it has anxiolytic and anticonvulsant effects but with little sedation or ataxia produced. (en) L'FG-8205 è uno psicofarmaco appartenente alla categoria delle ed è un analogo del bretazenil; esso agisce come un agonista parziale dei recettori GABA A, con leggera selettività per il sottotipo α1. Nei test sugli animali ha effetti ansiolitici e anticonvulsivanti ma con poca sedazione o atassia prodotta. (it)
rdfs:label	FG-8205 (en) FG-8205 (it)
owl:sameAs	freebase:FG-8205 yago-res:FG-8205 wikidata:FG-8205 dbpedia-it:FG-8205 dbpedia-sh:FG-8205 dbpedia-sr:FG-8205 https://global.dbpedia.org/id/4jJnH
prov:wasDerivedFrom	wikipedia-en:FG-8205?oldid=1120043607&ns=0
foaf:depiction	wiki-commons:Special:FilePath/FG-8205.svg
foaf:isPrimaryTopicOf	wikipedia-en:FG-8205
is dbo:wikiPageRedirects of	dbr:L-663,581
is dbo:wikiPageWikiLink of	dbr:List_of_benzodiazepines dbr:L-663,581
is foaf:primaryTopic of	wikipedia-en:FG-8205