About: Examples of in vivo transdifferentiation by lineage-instructive approach

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A list of examples of in vivo transdifferentiation through transfection: * mouse hepatocytes → B cells (Pdx1) * exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A) * nonsensory cells → inner hair cells (Atoh1 and MathI) * non cardiogenic mesoderm → cardiomyocytes (Gata4, Tbx5 and Smarcd3 or Baf60c) Through excision: * B-cell precursors → hematopoietic progenitors(-Pax5) * In adult ovarian follicles, granulosa and thecal cells → functional Sertoli-like and Leydig-like cells (-Foxl1)

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  • A list of examples of in vivo transdifferentiation through transfection: * mouse hepatocytes → B cells (Pdx1) * exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A) * nonsensory cells → inner hair cells (Atoh1 and MathI) * non cardiogenic mesoderm → cardiomyocytes (Gata4, Tbx5 and Smarcd3 or Baf60c) Through excision: * B-cell precursors → hematopoietic progenitors(-Pax5) * In adult ovarian follicles, granulosa and thecal cells → functional Sertoli-like and Leydig-like cells (-Foxl1) (en)
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  • A list of examples of in vivo transdifferentiation through transfection: * mouse hepatocytes → B cells (Pdx1) * exocrine cells → B cells (Pdx1, Ngn3, and v-maf musculoaponeurotic fibrosarcoma oncogene family protein A) * nonsensory cells → inner hair cells (Atoh1 and MathI) * non cardiogenic mesoderm → cardiomyocytes (Gata4, Tbx5 and Smarcd3 or Baf60c) Through excision: * B-cell precursors → hematopoietic progenitors(-Pax5) * In adult ovarian follicles, granulosa and thecal cells → functional Sertoli-like and Leydig-like cells (-Foxl1) (en)
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  • Examples of in vivo transdifferentiation by lineage-instructive approach (en)
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