| dbo:abstract
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- Estradiol benzoate/progesterone (EB/P4), sold under the brand names Duogynon and Sistocyclin among others, is a combination medication of estradiol benzoate (EB), an estrogen, and progesterone (P4), a progestogen. It has been formulated both as short-acting oil solutions and long-acting microcrystalline aqueous suspensions and is given by injection into muscle either once or continuously at regular intervals. EB/P4 was one of the first combined estrogen and progestogen medications to be introduced for medical use. It was first marketed in Germany as an oil solution in 1950. Microcrystalline EB/P4 in aqueous suspension was developed and marketed under the brand name Sistocyclin several years later. EB/P4 was eventually superseded by longer-acting parenteral estrogen–progestogen combinations as well as by oral estrogen–progestogen combinations. (en)
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| dbo:alternativeName
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- Clinomin Forte, Duogynon, Lutrogen, Sistocyclin, Vermagest, others (en)
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| dbo:casNumber
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- (mixture)
- 50-50-0
- 57-83-0
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| dbo:pubchem
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- 22383 (xsd:nonNegativeInteger)
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| dbp:caption
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| dbp:casNumber
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- 50 (xsd:integer)
- 57 (xsd:integer)
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| dbp:casSupplemental
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| dbp:chemspiderid
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| dbp:class
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| dbp:component
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- Progesterone (en)
- Estradiol benzoate (en)
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| dbp:image
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| dbp:pubchem
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| dbp:routesOfAdministration
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- Intramuscular injection (en)
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| dbp:synonyms
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| dbp:tradename
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- Clinomin Forte, Duogynon, Lutrogen, Sistocyclin, Vermagest, others (en)
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- 1 (xsd:integer)
- 4 (xsd:integer)
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- 225 (xsd:integer)
- 250 (xsd:integer)
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| rdfs:comment
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- Estradiol benzoate/progesterone (EB/P4), sold under the brand names Duogynon and Sistocyclin among others, is a combination medication of estradiol benzoate (EB), an estrogen, and progesterone (P4), a progestogen. It has been formulated both as short-acting oil solutions and long-acting microcrystalline aqueous suspensions and is given by injection into muscle either once or continuously at regular intervals. (en)
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| rdfs:label
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- Estradiol benzoate/progesterone (en)
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