Edward Joseph O'Donnell (April 13, 1907 – December 9, 1991) was an American naval officer. He commanded the Guantanamo Bay Naval Base from December 1960 to 1963, during which the Bay of Pigs Invasion and the Cuban Missile Crisis occurred. He then served as senior navy member of the Military Studies and Liaison division at The Pentagon and superintendent of the Naval Postgraduate School before retiring as a rear admiral in 1967. After retirement, O'Donnell was president of the New York Maritime College until 1972.