Edwin Karger (May 6, 1883 – September 9, 1957) was a pitcher in Major League Baseball from 1906 to 1911. He played for the Pittsburgh Pirates, St. Louis Cardinals, Cincinnati Reds, and Boston Red Sox. Karger finished his career with a 48–67 win–loss record and a 2.79 earned run average. As a hitter, he was better than average for a pitcher, posting a .220 batting average (88-for-400) with 6 home runs and 35 RBI. On August 11, 1907 in a game against the Boston Doves, Karger was given credit for a seven inning perfect game. Karger lived in Alaska in the early 1940s.