An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, DMTB, trade names Ohton, Aminobutene, Dimethibutin, Kobaton, Takaton, Dimethibutin) is an opioid analgesic drug, most often used in veterinary medicine in Japan and to a lesser extent in other countries in the region and around the world. It is the most prominent and widely used of the thiambutenes, a series of open-chain opioids structurally related to methadone which are also called the thienyl derivative opioids which also includes diethylthiambutene and ethylmethylthiambutene, as well as the non-opioid cough suppressant tipepidine.

Property Value
dbo:abstract
  • Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, DMTB, trade names Ohton, Aminobutene, Dimethibutin, Kobaton, Takaton, Dimethibutin) is an opioid analgesic drug, most often used in veterinary medicine in Japan and to a lesser extent in other countries in the region and around the world. It is the most prominent and widely used of the thiambutenes, a series of open-chain opioids structurally related to methadone which are also called the thienyl derivative opioids which also includes diethylthiambutene and ethylmethylthiambutene, as well as the non-opioid cough suppressant tipepidine. Dimethylthiambutene was developed in the United Kingdom in the late 1940s and introduced to the market by Burroughs-Wellcome in 1951. Dimethylthiambutene is now under international control under the UN Single Convention on Narcotic Drugs 1961, the laws governing habit-forming substances in virtually all countries and Schedule I of the US Controlled Substances Act of 1970 due to high abuse potential and never being introduced clinically in the United States; other countries regulate it much as morphine or diamorphine. Its DEA ACSCN is 9619 and it had a zero manufacturing quota in 2013. (en)
  • Dimetylotiambuten – organiczny związek chemiczny stosowany jako syntetyczny lek opioidowy. Jest objęty Jednolitą konwencją o środkach odurzających z 1961 roku (wykaz I). W Polsce jest w wykazie I-N Ustawy o przeciwdziałaniu narkomanii. (pl)
  • Dimetyltiambuten, summaformel C14H17NS2, är ett smärtstillande preparat som tillhör gruppen opioider. Preparatet används inte som läkemedel i Sverige. Substansen är narkotikaklassad och ingår i förteckningen N I i 1961 års allmänna narkotikakonvention, samt i förteckning II i Sverige. (sv)
dbo:casNumber
  • 524-84-5
dbo:chEBI
  • 59781
dbo:chEMBL
  • 2106265
dbo:drugbank
  • DB01444
dbo:fdaUniiCode
  • 915D88LM9O
dbo:pubchem
  • 10668
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  • 2106265 (xsd:integer)
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  • 10218 (xsd:integer)
dbp:drugbank
  • DB01444 (en)
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  • 17 (xsd:integer)
dbp:image
  • DMTB_3D.png (en)
dbp:iupacName
  • -N,N-dimethyl-4,4-dithiophen-2-yl-but-3-en-2-amine (en)
dbp:legalCa
  • Schedule I (en)
dbp:legalDe
  • Anlage I (en)
dbp:legalUs
  • Schedule I (en)
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  • 170 (xsd:integer)
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  • 169 (xsd:integer)
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  • CCNC (en)
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rdfs:comment
  • Dimetylotiambuten – organiczny związek chemiczny stosowany jako syntetyczny lek opioidowy. Jest objęty Jednolitą konwencją o środkach odurzających z 1961 roku (wykaz I). W Polsce jest w wykazie I-N Ustawy o przeciwdziałaniu narkomanii. (pl)
  • Dimetyltiambuten, summaformel C14H17NS2, är ett smärtstillande preparat som tillhör gruppen opioider. Preparatet används inte som läkemedel i Sverige. Substansen är narkotikaklassad och ingår i förteckningen N I i 1961 års allmänna narkotikakonvention, samt i förteckning II i Sverige. (sv)
  • Dimethylthiambutene (N,N-Dimethyl-1-methyl-3,3-di-2-thienylallylamine, DMTB, trade names Ohton, Aminobutene, Dimethibutin, Kobaton, Takaton, Dimethibutin) is an opioid analgesic drug, most often used in veterinary medicine in Japan and to a lesser extent in other countries in the region and around the world. It is the most prominent and widely used of the thiambutenes, a series of open-chain opioids structurally related to methadone which are also called the thienyl derivative opioids which also includes diethylthiambutene and ethylmethylthiambutene, as well as the non-opioid cough suppressant tipepidine. (en)
rdfs:label
  • Dimethylthiambutene (en)
  • Dimetylotiambuten (pl)
  • Dimetyltiambuten (sv)
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