About: Dienolone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Dienolone (developmental code name RU-3118; online product names Trenazone, Dienazone), or nordienolone, also known as 19-nor-δ9(10)-testosterone, δ9(10)-nandrolone, or estra-4,9(10)-dien-17β-ol-3-one, is a synthetic anabolic-androgenic steroid (AAS) of the 19-nortestosterone group that was never marketed. It has been found to possess slightly lower affinity for the androgen receptor (AR) and progesterone receptor (PR) relative to nandrolone in rat and rabbit tissue bioassays, whereas trenbolone was found to possess the same affinity for the AR as dienolone but several-fold increased affinity for the PR. Dienedione (the 17-keto analogue of dienolone, also known as 19-nor-4,9-androstadienedione) is thought to be a prohormone of dienolone, while methyldienolone and ethyldienolone are orally

Property	Value
dbo:abstract	Dienolone (developmental code name RU-3118; online product names Trenazone, Dienazone), or nordienolone, also known as 19-nor-δ9(10)-testosterone, δ9(10)-nandrolone, or estra-4,9(10)-dien-17β-ol-3-one, is a synthetic anabolic-androgenic steroid (AAS) of the 19-nortestosterone group that was never marketed. It has been found to possess slightly lower affinity for the androgen receptor (AR) and progesterone receptor (PR) relative to nandrolone in rat and rabbit tissue bioassays, whereas trenbolone was found to possess the same affinity for the AR as dienolone but several-fold increased affinity for the PR. Dienedione (the 17-keto analogue of dienolone, also known as 19-nor-4,9-androstadienedione) is thought to be a prohormone of dienolone, while methyldienolone and ethyldienolone are orally active 17α-alkylated AAS derivatives of dienolone. In contrast, dienogest, the 17α-cyanomethyl derivative of dienolone, is a potent progestogen and antiandrogen. (en)
dbo:casNumber	6218-29-7
dbo:chEMBL	2311179
dbo:fdaUniiCode	ZX4VV1AKUF
dbo:pubchem	11747706
dbo:thumbnail	wiki-commons:Special:FilePath/Dienolone_structure.png?width=300
dbo:wikiPageID	51759503 (xsd:integer)
dbo:wikiPageLength	4897 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1088400641 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Progestogen dbr:Androgen_prohormone dbr:Androgen_receptor dbr:Cyanomethyl dbr:Structural_analog dbc:Androgens_and_anabolic_steroids dbc:Conjugated_dienes dbc:Enones dbc:Estranes dbc:Progestogens dbr:Oral_administration dbr:Antiandrogen dbr:Progesterone_receptor dbr:Trenbolone dbr:Ethyldienolone dbr:Affinity_(pharmacology) dbr:Bioassay dbr:Tissue_(biology) dbr:Dienedione dbr:Dienogest dbr:Methyldienolone dbr:Nandrolone dbr:Rabbit dbr:Rat dbr:19-nortestosterone dbr:Anabolic-androgenic_steroid dbr:Synthetic_compound dbr:17α-alkylated_anabolic_steroid
dbp:atcPrefix	None (en)
dbp:c	18 (xsd:integer)
dbp:casNumber	6218 (xsd:integer)
dbp:chembl	2311179 (xsd:integer)
dbp:chemspiderid	9922410 (xsd:integer)
dbp:h	24 (xsd:integer)
dbp:iupacName	-17 (xsd:integer)
dbp:o	2 (xsd:integer)
dbp:pubchem	11747706 (xsd:integer)
dbp:smiles	CC12CCC3=C4CCCC=C4CCC3C1CCC2O (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	PUQSDJZESAQGQS-OWSLCNJRSA-N (en)
dbp:synonyms	RU-3118; Nordienolone (en)
dbp:unii	ZX4VV1AKUF (en)
dbp:width	250 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Androgen_receptor_modulators dbt:Drugbox dbt:Progesterone_receptor_modulators dbt:Reflist dbt:Short_description
dcterms:subject	dbc:Androgens_and_anabolic_steroids dbc:Conjugated_dienes dbc:Enones dbc:Estranes dbc:Progestogens
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 dbo:Drug
rdfs:comment	Dienolone (developmental code name RU-3118; online product names Trenazone, Dienazone), or nordienolone, also known as 19-nor-δ9(10)-testosterone, δ9(10)-nandrolone, or estra-4,9(10)-dien-17β-ol-3-one, is a synthetic anabolic-androgenic steroid (AAS) of the 19-nortestosterone group that was never marketed. It has been found to possess slightly lower affinity for the androgen receptor (AR) and progesterone receptor (PR) relative to nandrolone in rat and rabbit tissue bioassays, whereas trenbolone was found to possess the same affinity for the AR as dienolone but several-fold increased affinity for the PR. Dienedione (the 17-keto analogue of dienolone, also known as 19-nor-4,9-androstadienedione) is thought to be a prohormone of dienolone, while methyldienolone and ethyldienolone are orally (en)
rdfs:label	Dienolone (en)
owl:sameAs	yago-res:Dienolone wikidata:Dienolone https://global.dbpedia.org/id/2Z1GY
prov:wasDerivedFrom	wikipedia-en:Dienolone?oldid=1088400641&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Dienolone_structure.png
foaf:isPrimaryTopicOf	wikipedia-en:Dienolone
is dbo:wikiPageRedirects of	dbr:Nordienolone dbr:9(10)-Nandrolone dbr:9(10)-nandrolone dbr:R-3118 dbr:R3118 dbr:RU-3118 dbr:RU3118 dbr:RU_3118 dbr:R_3118
is dbo:wikiPageWikiLink of	dbr:List_of_androgens/anabolic_steroids_(alternate) dbr:List_of_androgens_and_anabolic_steroids dbr:Nordienolone dbr:C18H24O2 dbr:Ethyldienolone dbr:Dienedione dbr:Dienogest dbr:Methyldienolone dbr:Nandrolone dbr:9(10)-Nandrolone dbr:9(10)-nandrolone dbr:R-3118 dbr:R3118 dbr:RU-3118 dbr:RU3118 dbr:RU_3118 dbr:R_3118
is foaf:primaryTopic of	wikipedia-en:Dienolone