Diana Kanzira Atwine (born in 1973), also Diana Atwiine, is a Ugandan medical doctor and civil servant. She is the incumbent Permanent Secretary of the Uganda Ministry of Health. She was appointed to that position on 4 November 2016 by Yoweri Museveni, the president of Uganda. She replaced Dr. Asumani Lukwago, who was transferred as Permanent Secretary to the Education Services Commission.