About: Desmoplastic fibroma

In medicine, a desmoplastic fibroma is a benign, but locally aggressive, fibrous and rare tumor of the bone, affecting children and young adults, potentially resulting in cortical bone destruction. It usually affects craniofacial bones, mandible most frequently, long bones (metaphyseal femur, tibia, humerus). The World Health Organization, 2020, reclassified these tumors as specific benign tumors in the category of fibroblastic and myofibroblastic tumors. Some cases have been described, in which an osteosarcoma has arisen from a desmoplastic fibroma.