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- Desoxypyridinolin ist ein Abbauprodukt des Knochen-Kollagens. Es wird über die Nieren im Urin ausgeschieden. Die Indikation zur Untersuchung auf diese Substanz ergibt sich aus einer Fragestellung nach einer erhöhten Knochenumbaurate. Die Konzentration von Desoxypyridinolin im Urin ist beispielsweise beim primären Hyperparathyreoidismus, Knochenmetastasen und Morbus Paget erhöht. (de)
- Deoxypyridinoline, also called D-Pyrilinks, Pyrilinks-D, or deoxyPYD, is one of two pyridinium cross-links that provide structural stiffness to type I collagen found in bones. It is excreted unmetabolized in urine and is a specific marker of bone resorption and osteoclastic activity. It is measured in urine tests and is used along with other bone markers such as alkaline phosphatase, osteocalcin, and N-terminal telopeptide to diagnose bone diseases such as postmenopausal osteoporosis, bone metastasis, and Paget's disease, furthermore, it has been useful in monitoring treatments that contain bone-active agents such as estrogens and bisphosphonates. Certain studies have attempted to generate a standardization of Deoxypyridinoline via an individual molar absorptivity value at acid and neutrality pH. The result was 5160 and 5290 L mol−1 cm−1 respectively. (en)
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- (2R)-6-{3-[(3S)-3-Amino-4-hydroxy-4-oxobutyl]-4-[(2S)-2-amino-3-hydroxy-3-oxopropyl]-5-hydroxypyridin-1-ium-1-yl}hexanoate (en)
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- 2375 (xsd:nonNegativeInteger)
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- Deoxypyridinoline.svg (en)
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- Desoxypyridinolin ist ein Abbauprodukt des Knochen-Kollagens. Es wird über die Nieren im Urin ausgeschieden. Die Indikation zur Untersuchung auf diese Substanz ergibt sich aus einer Fragestellung nach einer erhöhten Knochenumbaurate. Die Konzentration von Desoxypyridinolin im Urin ist beispielsweise beim primären Hyperparathyreoidismus, Knochenmetastasen und Morbus Paget erhöht. (de)
- Deoxypyridinoline, also called D-Pyrilinks, Pyrilinks-D, or deoxyPYD, is one of two pyridinium cross-links that provide structural stiffness to type I collagen found in bones. It is excreted unmetabolized in urine and is a specific marker of bone resorption and osteoclastic activity. It is measured in urine tests and is used along with other bone markers such as alkaline phosphatase, osteocalcin, and N-terminal telopeptide to diagnose bone diseases such as postmenopausal osteoporosis, bone metastasis, and Paget's disease, furthermore, it has been useful in monitoring treatments that contain bone-active agents such as estrogens and bisphosphonates. (en)
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- Desoxypyridinolin (de)
- Deoxypyridinoline (en)
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