About: Daf-1

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The DAF-1 gene encodes for a cell surface Enzyme-linked receptor of TGF-beta signaling pathway in the worm Caenorhabditis elegans. DAF-1 is one of the type I receptor of TGF-beta pathway. DAF-1 acts as a receptor protein serine/threonine kinase, is activated by type II receptor Daf-4 phosphorylation after the ligand Daf-7 binds to the receptor heterotetramer, and then phosphorylates Daf-8 or Daf-14, the SMAD proteins in C. elegans.

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dbo:abstract
  • The DAF-1 gene encodes for a cell surface Enzyme-linked receptor of TGF-beta signaling pathway in the worm Caenorhabditis elegans. DAF-1 is one of the type I receptor of TGF-beta pathway. DAF-1 acts as a receptor protein serine/threonine kinase, is activated by type II receptor Daf-4 phosphorylation after the ligand Daf-7 binds to the receptor heterotetramer, and then phosphorylates Daf-8 or Daf-14, the SMAD proteins in C. elegans. (en)
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  • 2279 (xsd:nonNegativeInteger)
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  • 1109763236 (xsd:integer)
dbo:wikiPageWikiLink
dbp:chromosome
  • IV (en)
dbp:entrezgene
  • 176829 (xsd:integer)
dbp:genlocEnd
  • 138076 (xsd:integer)
dbp:genlocStart
  • 132416 (xsd:integer)
dbp:homologene
  • 134382 (xsd:integer)
dbp:name
  • abnormal dauer formation protein 1 (en)
dbp:organism
  • Caenorhabditis elegans (en)
dbp:symbol
  • daf-1 (en)
dbp:taxid
  • 6239 (xsd:integer)
dbp:uniprot
  • P20792 (en)
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rdfs:comment
  • The DAF-1 gene encodes for a cell surface Enzyme-linked receptor of TGF-beta signaling pathway in the worm Caenorhabditis elegans. DAF-1 is one of the type I receptor of TGF-beta pathway. DAF-1 acts as a receptor protein serine/threonine kinase, is activated by type II receptor Daf-4 phosphorylation after the ligand Daf-7 binds to the receptor heterotetramer, and then phosphorylates Daf-8 or Daf-14, the SMAD proteins in C. elegans. (en)
rdfs:label
  • Daf-1 (en)
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