About: Cystathionine gamma-synthase

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In enzymology, a cystathionine gamma-synthase (EC 2.5.1.48) is an enzyme that catalyzes the formation of cystathionine from cysteine and an activated derivative of homoserine, e.g.: O4-succinyl-L-homoserine + L-cysteine L-cystathionine + succinate In microorganisms, the activated substrate of this enzyme is or . Cystathionine gamma-synthase from plants uses instead.

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  • In enzymology, a cystathionine gamma-synthase (EC 2.5.1.48) is an enzyme that catalyzes the formation of cystathionine from cysteine and an activated derivative of homoserine, e.g.: O4-succinyl-L-homoserine + L-cysteine L-cystathionine + succinate In microorganisms, the activated substrate of this enzyme is or . Cystathionine gamma-synthase from plants uses instead. This enzyme belongs to the family of transferases, specifically those transferring aryl or alkyl groups other than methyl groups. The systematic name of this enzyme class is O4-succinyl-L-homoserine:L-cysteine S-(3-amino-3-carboxypropyl)transferase. Other names in common use include O-succinyl-L-homoserine succinate-lyase (adding cysteine), O-succinylhomoserine (thiol)-lyase, homoserine O-transsuccinylase, O-succinylhomoserine synthase, O-succinylhomoserine synthetase, cystathionine synthase, cystathionine synthetase, homoserine transsuccinylase, 4-O-succinyl-L-homoserine:L-cysteine, and S-(3-amino-3-carboxypropyl)transferase. This enzyme participates in 4 metabolic pathways: methionine metabolism, cysteine metabolism, , and sulfur metabolism. It employs one cofactor, pyridoxal phosphate. (en)
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  • 2.5.1.48
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  • 14545726 (xsd:integer)
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  • Cystathionine gamma-synthase homotetramer, Helicobacter pylori (en)
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  • 9030 (xsd:integer)
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  • 2.500000 (xsd:double)
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  • 3962 (xsd:integer)
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  • 2 (xsd:integer)
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  • cystathionine gamma-synthase (en)
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  • In enzymology, a cystathionine gamma-synthase (EC 2.5.1.48) is an enzyme that catalyzes the formation of cystathionine from cysteine and an activated derivative of homoserine, e.g.: O4-succinyl-L-homoserine + L-cysteine L-cystathionine + succinate In microorganisms, the activated substrate of this enzyme is or . Cystathionine gamma-synthase from plants uses instead. (en)
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  • Cystathionine gamma-synthase (en)
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  • cystathionine gamma-synthase (en)
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