| dbo:abstract
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- Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene (cyc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism. The cyc gene is located on the left arm of chromosome 3 and codes for a transcription factor containing a basic helix-loop-helix (bHLH) domain and a PAS domain. The 2.17 kb cyc gene is divided into 5 coding exons totaling 1,625 base pairs which code for 413 aminos acid residues. Currently 19 alleles are known for cyc . Orthologs performing the same function in other species include ARNTL and ARNTL2. (en)
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- 23605 (xsd:nonNegativeInteger)
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- The approximate 3D structure of CYC protein generated with Phyre2. The protein sequence information was obtained from the UniProt database. (en)
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- 406 (xsd:integer)
- 40162 (xsd:integer)
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| dbp:name
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- Cycle (en)
- aryl hydrocarbon receptor nuclear translocator-like (en)
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- Drosophila melanogaster (en)
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| rdfs:comment
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- Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene (cyc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism. The cyc gene is located on the left arm of chromosome 3 and codes for a transcription factor containing a basic helix-loop-helix (bHLH) domain and a PAS domain. The 2.17 kb cyc gene is divided into 5 coding exons totaling 1,625 base pairs which code for 413 aminos acid residues. Currently 19 alleles are known for cyc . Orthologs performing the same function in other species include ARNTL and ARNTL2. (en)
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- aryl hydrocarbon receptor nuclear translocator-like (en)
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