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Corticotropin-like intermediate [lobe] peptide (CLIP), also known as adrenocorticotropic hormone fragment 18-39 (ACTH(18-39)), is a naturally occurring, endogenous neuropeptide with a docosapeptide structure and the amino acid sequence Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe. CLIP is generated as a proteolyic cleavage product of adrenocorticotropic hormone (ACTH), which in turn is a cleavage product of proopiomelanocortin (POMC). Its physiological role has been investigated in various tissues, specifically in the central nervous system.

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dbo:abstract
  • Corticotropin-like intermediate [lobe] peptide (CLIP), also known as adrenocorticotropic hormone fragment 18-39 (ACTH(18-39)), is a naturally occurring, endogenous neuropeptide with a docosapeptide structure and the amino acid sequence Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe. CLIP is generated as a proteolyic cleavage product of adrenocorticotropic hormone (ACTH), which in turn is a cleavage product of proopiomelanocortin (POMC). Its physiological role has been investigated in various tissues, specifically in the central nervous system. It has been suggested to function as an insulin secretagogue in the pancreas. (en)
  • El péptido del lóbulo intermedio semejante a la corticotropina, o CLIP (del inglés: corticotropin-like intermediate peptide) es un neuropéptido corto secretada por las células del adenohipófisis. Su precursor es la ACTH, cuyo precursor a su vez es la proopiomelanocortina. (es)
dbo:arm
  • p
dbo:band
  • 23
dbo:chromosome
  • 2
dbo:entrezgene
  • 5443
dbo:hgncid
  • 9201
dbo:omim
  • 176830 (xsd:integer)
dbo:refseq
  • NM_000939
dbo:symbol
  • POMC
dbo:thumbnail
dbo:uniprot
  • P01189
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  • 7162827 (xsd:integer)
dbo:wikiPageLength
  • 8457 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1116631497 (xsd:integer)
dbo:wikiPageWikiLink
dbp:arm
  • p (en)
dbp:band
  • 23 (xsd:integer)
dbp:chromosome
  • 2 (xsd:integer)
dbp:entrezgene
  • 5443 (xsd:integer)
dbp:hgncid
  • 9201 (xsd:integer)
dbp:imagefile
  • Corticotropin-like intermediate peptide.svg (en)
dbp:iupacname
  • (L)-arginyl-(L)-prolyl-(L)-valyl-(L)-lysyl-(L)-valyl-(L)-tyrosyl-(L)-prolyl-(L)-asparaginyl-(L)-glycyl-(L)-alanyl-(L)-α-glutamyl-(L)-α-aspartyl-(L)-α-glutamyl-(L)-seryl-(L)-alanyl-(L)-α-glutamyl-(L)-alanyl-(L)-phenylalanyl-(L)-prolyl-(L)-leucyl-(L)-α-glutamyl-(L)-phenylalanine (en)
dbp:name
dbp:omim
  • 176830 (xsd:integer)
dbp:refseq
  • NM_000939 (en)
dbp:symbol
  • POMC (en)
dbp:uniprot
  • P01189 (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • El péptido del lóbulo intermedio semejante a la corticotropina, o CLIP (del inglés: corticotropin-like intermediate peptide) es un neuropéptido corto secretada por las células del adenohipófisis. Su precursor es la ACTH, cuyo precursor a su vez es la proopiomelanocortina. (es)
  • Corticotropin-like intermediate [lobe] peptide (CLIP), also known as adrenocorticotropic hormone fragment 18-39 (ACTH(18-39)), is a naturally occurring, endogenous neuropeptide with a docosapeptide structure and the amino acid sequence Arg-Pro-Val-Lys-Val-Tyr-Pro-Asn-Gly-Ala-Glu-Asp-Glu-Ser-Ala-Glu-Ala-Phe-Pro-Leu-Glu-Phe. CLIP is generated as a proteolyic cleavage product of adrenocorticotropic hormone (ACTH), which in turn is a cleavage product of proopiomelanocortin (POMC). Its physiological role has been investigated in various tissues, specifically in the central nervous system. (en)
rdfs:label
  • Péptido del lóbulo intermedio semejante a la corticotropina (es)
  • Corticotropin-like intermediate peptide (en)
owl:sameAs
prov:wasDerivedFrom
foaf:depiction
foaf:isPrimaryTopicOf
foaf:name
  • pro-opiomelanocortin (en)
is dbo:wikiPageDisambiguates of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
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