About: Conorfone

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Conorfone (INN; TR-5109), also known as conorphone and codorphone, as well as conorphone hydrochloride (USAN), is an opioid analgesic that was never marketed. It is an analogue of hydrocodone substituted with an 8-ethyl group and an N-cyclopropylmethyl group. It acts as a mixed agonist-antagonist at the μ-opioid receptor, and is slightly more potent than codeine in analgesic effects but associated with somewhat greater side effects.

Property	Value
dbo:abstract	Conorfone (INN; TR-5109), also known as conorphone and codorphone, as well as conorphone hydrochloride (USAN), is an opioid analgesic that was never marketed. It is an analogue of hydrocodone substituted with an 8-ethyl group and an N-cyclopropylmethyl group. It acts as a mixed agonist-antagonist at the μ-opioid receptor, and is slightly more potent than codeine in analgesic effects but associated with somewhat greater side effects. (en)
dbo:casNumber	72060-05-0
dbo:chEMBL	2106064
dbo:fdaUniiCode	9H58696D23
dbo:pubchem	172964
dbo:thumbnail	wiki-commons:Special:FilePath/Conorfone2DCSD.svg?width=300
dbo:wikiPageID	20035128 (xsd:integer)
dbo:wikiPageLength	3651 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1090160428 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Partial_agonist dbr:Hydrocodone dbr:Von_Braun_reaction dbc:4,5-Epoxymorphinans dbc:Analgesics dbc:Cyclopropanes dbc:Ketones dbc:Mu-opioid_receptor_agonists dbc:Semisynthetic_opioids dbr:Codeine dbr:Analgesic dbc:Catechol_ethers dbr:Cyanogen_bromide dbr:Receptor_(biochemistry) dbr:International_Nonproprietary_Name dbr:Methyl dbr:Opioid dbr:Side_effect dbr:United_States_Adopted_Name dbr:Ethyl_group dbr:Mu_opioid_receptor dbr:Analog_(chemistry) dbr:Cyclopropyl dbr:Cyclopropylmethyl_chloride dbr:File:Codorphone_synthesis.svg
dbp:atcPrefix	None (en)
dbp:c	23 (xsd:integer)
dbp:casNumber	72060 (xsd:integer)
dbp:chembl	2106064 (xsd:integer)
dbp:chemspiderid	151049 (xsd:integer)
dbp:h	29 (xsd:integer)
dbp:iupacName	-17 (xsd:integer)
dbp:n	1 (xsd:integer)
dbp:o	3 (xsd:integer)
dbp:pubchem	172964 (xsd:integer)
dbp:smiles	O=C4[C@@H]5Oc1c2cCC3NCC6CC6 (en)
dbp:unii	9 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Analgesic-stub dbt:Analgesics dbt:Drugbox dbt:Opioidergics dbt:Reflist dbt:Short_description dbt:Fdacite
dct:subject	dbc:4,5-Epoxymorphinans dbc:Analgesics dbc:Cyclopropanes dbc:Ketones dbc:Mu-opioid_receptor_agonists dbc:Semisynthetic_opioids dbc:Catechol_ethers
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:Abstraction100002137 yago:Chemical114806838 yago:Compound114818238 yago:Element114840755 yago:Ketone114926294 yago:Material114580897 yago:Matter100020827 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Quintessence114847103 yago:Relation100031921 yago:WikicatKetones dbo:Drug yago:Substance100019613 yago:WikicatPhenolEthers umbel-rc:DrugProduct
rdfs:comment	Conorfone (INN; TR-5109), also known as conorphone and codorphone, as well as conorphone hydrochloride (USAN), is an opioid analgesic that was never marketed. It is an analogue of hydrocodone substituted with an 8-ethyl group and an N-cyclopropylmethyl group. It acts as a mixed agonist-antagonist at the μ-opioid receptor, and is slightly more potent than codeine in analgesic effects but associated with somewhat greater side effects. (en)
rdfs:label	Conorfone (en)
owl:sameAs	freebase:Conorfone yago-res:Conorfone wikidata:Conorfone dbpedia-sh:Conorfone dbpedia-sr:Conorfone https://global.dbpedia.org/id/4iKsf
prov:wasDerivedFrom	wikipedia-en:Conorfone?oldid=1090160428&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Codorphone_synthesis.svg wiki-commons:Special:FilePath/Conorfone2DCSD.svg
foaf:isPrimaryTopicOf	wikipedia-en:Conorfone
is dbo:wikiPageRedirects of	dbr:Conorfone_hydrochloride dbr:Conorphone dbr:Conorphone_hydrochloride dbr:Codorfone dbr:Codorfone_hydrochloride dbr:Codorphone dbr:Codorphone_hydrochloride dbr:TR-5109 dbr:TR5109 dbr:TR_5109
is dbo:wikiPageWikiLink of	dbr:List_of_opioids dbr:List_of_drugs:_Cm–Co dbr:Conorfone_hydrochloride dbr:Conorphone dbr:Conorphone_hydrochloride dbr:Codorfone dbr:Codorfone_hydrochloride dbr:Codorphone dbr:Codorphone_hydrochloride dbr:TR-5109 dbr:TR5109 dbr:TR_5109
is foaf:primaryTopic of	wikipedia-en:Conorfone