About: Complement 3 deficiency

An Entity of Type: disease, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Complement 3 deficiency is a genetic condition affecting complement component 3 (C3). People can suffer from either primary or secondary C3 deficiency. Primary C3 deficiency refers to an inherited autosomal-recessive disorder that involves mutations in the gene for C3. Secondary C3 deficiency results from a lack of factor I or factor H, two proteins that are key for the regulation of C3. Both primary and secondary C3 deficiency are characterized by low levels or absence of C3.

Property	Value
dbo:abstract	Complement 3 deficiency is a genetic condition affecting complement component 3 (C3). People can suffer from either primary or secondary C3 deficiency. Primary C3 deficiency refers to an inherited autosomal-recessive disorder that involves mutations in the gene for C3. Secondary C3 deficiency results from a lack of factor I or factor H, two proteins that are key for the regulation of C3. Both primary and secondary C3 deficiency are characterized by low levels or absence of C3. (en)
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dbo:wikiPageWikiLink	dbr:Innate_immune_system dbr:Interleukin_6 dbr:Complement_system dbr:Membranoproliferative_glomerulonephritis dbr:Complement_component_3 dbr:Complement_factor_I dbr:C3-convertase dbr:Adaptive_immune_system dbr:Tumor_necrosis_factor_alpha dbr:Lectin_pathway dbr:Lipopolysaccharide dbr:Alternative_complement_pathway dbc:Complement_deficiency dbr:Bacterial_capsule dbr:Systemic_lupus_erythematosus dbr:Classical_complement_pathway dbr:Interferon_gamma dbr:Interleukin-1_family dbr:Factor_H
dbp:diseasesdb	1869 (xsd:integer)
dbp:field	immunology (en)
dbp:name	Complement 3 deficiency (en)
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gold:hypernym	dbr:Condition
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rdfs:comment	Complement 3 deficiency is a genetic condition affecting complement component 3 (C3). People can suffer from either primary or secondary C3 deficiency. Primary C3 deficiency refers to an inherited autosomal-recessive disorder that involves mutations in the gene for C3. Secondary C3 deficiency results from a lack of factor I or factor H, two proteins that are key for the regulation of C3. Both primary and secondary C3 deficiency are characterized by low levels or absence of C3. (en)
rdfs:label	Complement 3 deficiency (en)
owl:sameAs	freebase:Complement 3 deficiency wikidata:Complement 3 deficiency https://global.dbpedia.org/id/4i1Pr
prov:wasDerivedFrom	wikipedia-en:Complement_3_deficiency?oldid=997937126&ns=0
foaf:isPrimaryTopicOf	wikipedia-en:Complement_3_deficiency
foaf:name	Complement 3 deficiency (en)
is foaf:primaryTopic of	wikipedia-en:Complement_3_deficiency