About: Codeine-6-glucuronide

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Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. C6G exhibits decreased immunosuppressive effects compared to codeine. During its metabolism, codeine is conjugated with glucuronic acid by the enzyme UDP-Glucuronosyltransferase-2B7 (UGT2B7) to form codeine-6-glucuronide.

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  • Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. C6G exhibits decreased immunosuppressive effects compared to codeine. During its metabolism, codeine is conjugated with glucuronic acid by the enzyme UDP-Glucuronosyltransferase-2B7 (UGT2B7) to form codeine-6-glucuronide. (en)
  • 6-Glukuronid kodeiny (K6G) – organiczny związek chemiczny, główny metabolit kodeiny.Powstaje on w wyniku połączenia się cząsteczek kodeiny i kwasu glukuronowego w obecności enzymu . (pl)
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  • (2S,3S,4S,5R,6R)-3,4,5-Trihydroxy-6-{[(4R,4aR,7S,7aR,12bS)-9-methoxy-3-methyl-2,3,4,4a,7,7a-hexahydro-1H-4,12-methano[1]benzofuro[3,2-e]isoquinolin-7-yl]oxy}oxane-2-carboxylic acid (en)
  • (5α,6α)-3-methoxy-17-methyl-7,8-didehydro-4,5-epoxymorphinan-6-yl β-D-glucopyranosiduronic acid (en)
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  • Codeine-6-glucuronide.svg (en)
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  • Codeine-6-glucuronide (C6G) is a major active metabolite of codeine and may be responsible for as much as 60% of the analgesic effects of codeine. C6G exhibits decreased immunosuppressive effects compared to codeine. During its metabolism, codeine is conjugated with glucuronic acid by the enzyme UDP-Glucuronosyltransferase-2B7 (UGT2B7) to form codeine-6-glucuronide. (en)
  • 6-Glukuronid kodeiny (K6G) – organiczny związek chemiczny, główny metabolit kodeiny.Powstaje on w wyniku połączenia się cząsteczek kodeiny i kwasu glukuronowego w obecności enzymu . (pl)
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  • Codeine-6-glucuronide (en)
  • 6-Glukuronid kodeiny (pl)
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