About: Clortermine

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Clortermine (Voranil) was developed by Ciba in the 1960s and is an anorectic drug of the amphetamine class. It is the 2-chloro analogue of the better known appetite suppressant phentermine, and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine, and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent.

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dbo:abstract
  • Clortermine (Voranil) was developed by Ciba in the 1960s and is an anorectic drug of the amphetamine class. It is the 2-chloro analogue of the better known appetite suppressant phentermine, and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine, and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent. (en)
  • La clortermina (Voranil) è stato sviluppato da Ciba negli anni '60 ed è un farmaco anoressizzante della classe delle anfetamine. È l'analogo 2- cloro della fentermina, un noto soppressore dell'appetito. La clortermina produce tassi molto bassi di autosomministrazione negli animali come la clorfentermina e di conseguenza probabilmente non agisce sulla dopamina. Invece, può agire come agente di rilascio della serotonina e/o della norepinefrina. (it)
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  • 10389-73-8
dbo:chEMBL
  • 1697833
dbo:drugbank
  • DB01527
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  • 4FA88HM3IX
dbo:kegg
  • D03566
dbo:pubchem
  • 25223
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  • D03566 (en)
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  • Rx-only (en)
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  • Schedule III (en)
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  • ? (en)
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  • 25223 (xsd:integer)
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dbp:smiles
  • Clc1ccccc1CCC (en)
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  • 1 (xsd:integer)
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  • HXCXASJHZQXCKK-UHFFFAOYSA-N (en)
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  • Clortermine (Voranil) was developed by Ciba in the 1960s and is an anorectic drug of the amphetamine class. It is the 2-chloro analogue of the better known appetite suppressant phentermine, and is the 2-chloro positional isomer of chlorphentermine. Clortermine produces very low rates of self-administration in animals similarly to chlorphentermine, and as a result it likely does not act on dopamine. Instead, it may act as a serotonin and/or norepinephrine releasing agent. (en)
  • La clortermina (Voranil) è stato sviluppato da Ciba negli anni '60 ed è un farmaco anoressizzante della classe delle anfetamine. È l'analogo 2- cloro della fentermina, un noto soppressore dell'appetito. La clortermina produce tassi molto bassi di autosomministrazione negli animali come la clorfentermina e di conseguenza probabilmente non agisce sulla dopamina. Invece, può agire come agente di rilascio della serotonina e/o della norepinefrina. (it)
rdfs:label
  • Clortermine (en)
  • Clortermina (it)
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