About: Cilofungin

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Cilofungin (INN) is the first clinically applied member of the echinocandin family of antifungal drugs. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the synthesis of (1→3)-β-D-glucan).

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dbo:abstract
  • Cilofungin (INN) is the first clinically applied member of the echinocandin family of antifungal drugs. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the synthesis of (1→3)-β-D-glucan). (en)
  • Cilofungin ist ein Antimykotikum aus der Gruppe der . Es hemmt die Zellwandbiosynthese bei manchen Candida-albicans-Arten. Wegen Toxizität der Trägersubstanz wurde die Entwicklung in Phase II eingestellt (Hersteller: Eli Lilly & Co.). (de)
dbo:alternativeName
  • 1-[(4R,5R)-4,5-Dihydroxy-N2-[p-(octyloxy)benzoyl]-(L)-ornithine]echinocandin B (en)
  • (4R,5R)-4,5-Dihydroxy-N2-[p-(octyloxy)benzoyl]-(L)-ornithyl-(L)-threonyl-trans-4-hydroxy-(L)-prolyl-(S)-4-hydroxy-4-(p-hydroxyphenyl)-(L)-threonyl-(L)-threonyl-(3S,4S)-3-hydroxy-4-methyl-(L)-proline cyclic (6→1)-peptide (en)
dbo:iupacName
  • N-[(11R,20R,21R,25S,26S)-6-[(1S,2S)-1,2-Dihydroxy-2-(4-hydroxyphenyl)ethyl]-11,20,21,25-tetrahydroxy-3,15-bis(1-hydroxyethyl)-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.09,13]heptacosan-18-yl]-4-(octyloxy)benzamide (en)
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  • Cilofungin.svg (en)
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  • N-[-6-[-1,2-Dihydroxy-2-ethyl]-11,20,21,25-tetrahydroxy-3,15-bis-26-methyl-2,5,8,14,17,23-hexaoxo-1,4,7,13,16,22-hexaazatricyclo[22.3.0.09,13]heptacosan-18-yl]-4-benzamide (en)
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  • Cilofungin (INN) is the first clinically applied member of the echinocandin family of antifungal drugs. It was derived from a fungus in the genus Aspergillus. It accomplishes this by interfering with an invading fungus' ability to synthesize the cell wall (specifically, it inhibits the synthesis of (1→3)-β-D-glucan). (en)
  • Cilofungin ist ein Antimykotikum aus der Gruppe der . Es hemmt die Zellwandbiosynthese bei manchen Candida-albicans-Arten. Wegen Toxizität der Trägersubstanz wurde die Entwicklung in Phase II eingestellt (Hersteller: Eli Lilly & Co.). (de)
rdfs:label
  • Cilofungin (de)
  • Cilofungin (en)
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