About: Cholesterol sulfate

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Cholesterol sulfate, or cholest-5-en-3β-ol sulfate, is an endogenous steroid and the C3β sulfate ester of cholesterol. It is formed from cholesterol by steroid sulfotransferases (SSTs) such as SULT2B1b (also known as cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of cholesterol sulfate in the skin is implicated in the pathophysiology of X-linked ichthyosis, a congenital disorder in which STS is non-functional and the body cannot convert cholesterol sulfate back into cholesterol.

Property	Value
dbo:abstract	Cholesterol sulfate, or cholest-5-en-3β-ol sulfate, is an endogenous steroid and the C3β sulfate ester of cholesterol. It is formed from cholesterol by steroid sulfotransferases (SSTs) such as SULT2B1b (also known as cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of cholesterol sulfate in the skin is implicated in the pathophysiology of X-linked ichthyosis, a congenital disorder in which STS is non-functional and the body cannot convert cholesterol sulfate back into cholesterol. (en)
dbo:alternativeName	Cholest-5-en-3β-ol sulfate (en)
dbo:iupacName	[(3S,8S,9S,10R,13R,14S,17R)-10,13-Dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate (en)
dbo:thumbnail	wiki-commons:Special:FilePath/Cholesterol_sulfate.svg?width=300
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dbo:wikiPageLength	2784 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	939527841 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Pathophysiology dbr:SULT2B1b dbc:Cholestanes dbr:Steroid_sulfatase dbc:Steroid_esters dbc:Sulfate_esters dbr:Ester dbr:Steroid dbr:Endogenous dbr:Cholesterol dbr:Sulfate dbr:Skin dbr:Congenital_disorder dbr:Steroid_sulfotransferase dbr:X-linked_ichthyosis dbr:Steroid_sulfate
dbp:imagefile	Cholesterol sulfate.svg (en)
dbp:imagesize	250 (xsd:integer)
dbp:iupacname	[-10,13-Dimethyl-17-[-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate (en)
dbp:othernames	Cholest-5-en-3β-ol sulfate (en)
dbp:wikiPageUsesTemplate	dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Endogenous_steroids dbt:Reflist dbt:Steroid-stub dbt:Cholesterol_and_steroid_intermediates
dcterms:subject	dbc:Cholestanes dbc:Steroid_esters dbc:Sulfate_esters
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound
rdfs:comment	Cholesterol sulfate, or cholest-5-en-3β-ol sulfate, is an endogenous steroid and the C3β sulfate ester of cholesterol. It is formed from cholesterol by steroid sulfotransferases (SSTs) such as SULT2B1b (also known as cholesterol sulfotransferase) and is converted back into cholesterol by steroid sulfatase (STS). Accumulation of cholesterol sulfate in the skin is implicated in the pathophysiology of X-linked ichthyosis, a congenital disorder in which STS is non-functional and the body cannot convert cholesterol sulfate back into cholesterol. (en)
rdfs:label	Cholesterol sulfate (en)
owl:sameAs	wikidata:Cholesterol sulfate https://global.dbpedia.org/id/2Y6M7
prov:wasDerivedFrom	wikipedia-en:Cholesterol_sulfate?oldid=939527841&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Cholesterol_sulfate.svg
foaf:isPrimaryTopicOf	wikipedia-en:Cholesterol_sulfate
is dbo:wikiPageRedirects of	dbr:C27H46O4S dbr:Cholest-5-en-3β-ol_sulfate dbr:Cholesterol-3-sulfate dbr:Cholesterol-sulfate dbr:Cholesterol_3-sulfate
is dbo:wikiPageWikiLink of	dbr:Steroid_sulfatase dbr:C27H46O4S dbr:Steroid_sulfotransferase dbr:X-linked_ichthyosis dbr:Steroid_sulfate dbr:Steroidogenesis_inhibitor dbr:Cholest-5-en-3β-ol_sulfate dbr:Cholesterol-3-sulfate dbr:Cholesterol-sulfate dbr:Cholesterol_3-sulfate
is foaf:primaryTopic of	wikipedia-en:Cholesterol_sulfate