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- In enzymology, a cholesterol oxidase (EC 1.1.3.6) is an enzyme that catalyzes the chemical reaction cholesterol + O2 cholest-4-en-3-one + H2O2 Thus, the two substrates of this enzyme are cholesterol and O2, whereas its two products are and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is cholesterol:oxygen oxidoreductase. Other names in common use include cholesterol- O2 oxidoreductase, 3beta-hydroxy steroid oxidoreductase, and 3beta-hydroxysteroid:oxygen oxidoreductase. This enzyme participates in bile acid biosynthesis. The substrate-binding domain found in some bacterial cholesterol oxidases is composed of an eight-stranded mixed beta-pleated sheet and six alpha-helices. This domain is positioned over the isoalloxazine ring system of the FAD cofactor bound by the FAD-binding domain and forms the roof of the active site cavity, allowing for catalysis of oxidation and isomerisation of cholesterol to cholest-4-en-3-one. (en)
- La colesterolo ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: colesterolo + O2 ⇄ colest-4-ene-3-one + H2O2 (it)
- コレステロールオキシダーゼ（cholesterol oxidase）は、ステロイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 コレステロール + O2 コレスト-4-エン-3-オン + H2O2 反応式の通り、この酵素の基質はコレステロールと酸素、生成物はと過酸化水素である。 組織名はcholesterol:oxygen oxidoreductaseで、別名にcholesterol- O2 oxidoreductase, 3β-hydroxy steroid oxidoreductase, 3β-hydroxysteroid:oxygen oxidoreductaseがある。 (ja)
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- 3772 (xsd:nonNegativeInteger)
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- crystal structure of cholesterol oxidase from b.sterolicum (en)
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- Cholesterol oxidase substrate-binding domain (en)
- cholesterol oxidase (en)
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- La colesterolo ossidasi è un enzima appartenente alla classe delle ossidoreduttasi, che catalizza la seguente reazione: colesterolo + O2 ⇄ colest-4-ene-3-one + H2O2 (it)
- コレステロールオキシダーゼ（cholesterol oxidase）は、ステロイド生合成酵素の一つで、次の化学反応を触媒する酸化還元酵素である。 コレステロール + O2 コレスト-4-エン-3-オン + H2O2 反応式の通り、この酵素の基質はコレステロールと酸素、生成物はと過酸化水素である。 組織名はcholesterol:oxygen oxidoreductaseで、別名にcholesterol- O2 oxidoreductase, 3β-hydroxy steroid oxidoreductase, 3β-hydroxysteroid:oxygen oxidoreductaseがある。 (ja)
- In enzymology, a cholesterol oxidase (EC 1.1.3.6) is an enzyme that catalyzes the chemical reaction cholesterol + O2 cholest-4-en-3-one + H2O2 Thus, the two substrates of this enzyme are cholesterol and O2, whereas its two products are and H2O2. (en)
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- Cholesterol oxidase (en)
- Colesterolo ossidasi (it)
- コレステロールオキシダーゼ (ja)
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