dbo:abstract
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- The Chemical Probes Portal is an open, online resource whose purpose is to identify and make available high quality chemical probes for use in biological research and drug discovery. While chemical probes can be valuable tools to elucidate signal transduction pathways and to validate new drug targets, many of the probes that are in use are not selective and therefore can give very misleading results. The Portal recommends chemical probes based on ratings provided by its Scientific Advisory Board (SAB), a group of experts in the fields of chemical biology, medicinal chemistry, and pharmacology, who (1) determine which are the best chemical probes available and (2) establish guidelines for using them. (en)
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- Increasing the quality and reproducibility of biomedical research using chemical probes.
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- 501(c)(3)nonprofit organization
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- 13588 (xsd:nonNegativeInteger)
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dbp:keyPeople
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- Paul Workman, Aled Edwards, Bissan Al-Lazikani, Ian Collins, Susanne Müller-Knapp, Albert A. Antolin, Domenico Sanfelice, Alisa Crisp (en)
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dbp:leaderName
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- Milka Kostic, Jonathan Baell, Alessio Ciulli, Jeremy L. Jenkins, Akane Kawamura, Yung Lie, Laetitia Martin, Osamu Nakanishi, Jonathan, S. Rosenblum, Jason Sheltzer (en)
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- Chemical Probes Portal (en)
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- Increasing the quality and reproducibility of biomedical research using chemical probes. (en)
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rdfs:comment
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- The Chemical Probes Portal is an open, online resource whose purpose is to identify and make available high quality chemical probes for use in biological research and drug discovery. While chemical probes can be valuable tools to elucidate signal transduction pathways and to validate new drug targets, many of the probes that are in use are not selective and therefore can give very misleading results. (en)
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- Chemical Probes Portal (en)
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- Chemical Probes Portal (en)
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