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Chalcone synthase or naringenin-chalcone synthase (CHS) is an enzyme ubiquitous to higher plants and belongs to a family of polyketide synthase enzymes (PKS) known as type III PKS. Type III PKSs are associated with the production of chalcones, a class of organic compounds found mainly in plants as natural defense mechanisms and as synthetic intermediates. CHS was the first type III PKS to be discovered. It is the first committed enzyme in flavonoid biosynthesis.The enzyme catalyzes the conversion of 4-coumaroyl-CoA and malonyl-CoA to naringenin chalcone.

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dbo:abstract
  • Chalcone synthase or naringenin-chalcone synthase (CHS) is an enzyme ubiquitous to higher plants and belongs to a family of polyketide synthase enzymes (PKS) known as type III PKS. Type III PKSs are associated with the production of chalcones, a class of organic compounds found mainly in plants as natural defense mechanisms and as synthetic intermediates. CHS was the first type III PKS to be discovered. It is the first committed enzyme in flavonoid biosynthesis.The enzyme catalyzes the conversion of 4-coumaroyl-CoA and malonyl-CoA to naringenin chalcone. (en)
  • La naringenina-calcone sintasi è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: 3 malonil-CoA + 4- ⇄ 4 CoA + naringenina calcone + 3 CO2 In presenza di NADH e di una , viene prodotto il 6'-deossicalcone. (it)
dbo:ecNumber
  • 2.3.1.74
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  • 9435887 (xsd:integer)
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  • 16364 (xsd:nonNegativeInteger)
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  • 997684313 (xsd:integer)
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dbp:caption
  • The structure of CHS from Medicago sativa. (en)
dbp:casNumber
  • 56803 (xsd:integer)
dbp:ecNumber
  • 2.300000 (xsd:double)
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  • 16210 (xsd:integer)
dbp:interpro
  • IPR012328 (en)
dbp:name
  • Chalcone Synthase (en)
  • Chalcone and stilbene synthases, C-terminal domain (en)
dbp:pfam
  • PF02797 (en)
dbp:pfamClan
  • CL0046 (en)
dbp:symbol
  • Chal_sti_synt_C (en)
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rdfs:comment
  • Chalcone synthase or naringenin-chalcone synthase (CHS) is an enzyme ubiquitous to higher plants and belongs to a family of polyketide synthase enzymes (PKS) known as type III PKS. Type III PKSs are associated with the production of chalcones, a class of organic compounds found mainly in plants as natural defense mechanisms and as synthetic intermediates. CHS was the first type III PKS to be discovered. It is the first committed enzyme in flavonoid biosynthesis.The enzyme catalyzes the conversion of 4-coumaroyl-CoA and malonyl-CoA to naringenin chalcone. (en)
  • La naringenina-calcone sintasi è un enzima appartenente alla classe delle transferasi, che catalizza la seguente reazione: 3 malonil-CoA + 4- ⇄ 4 CoA + naringenina calcone + 3 CO2 In presenza di NADH e di una , viene prodotto il 6'-deossicalcone. (it)
rdfs:label
  • Chalcone synthase (en)
  • Naringenina-calcone sintasi (it)
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foaf:isPrimaryTopicOf
foaf:name
  • (en)
  • Chalcone Synthase (Naringenin Chalcone Synthase) (en)
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