| dbo:abstract
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- Cdc4 (cell division control protein 4) is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which acts as a mediator of ubiquitin transfer to target proteins, leading to their subsequent degradation via the ubiquitin-proteasome pathway. Cdc4 targets primarily cell cycle regulators for proteolysis. It serves the function of an adaptor that brings target molecules to the core SCF complex. Cdc4 was originally identified in the model organism Saccharomyces cerevisiae. CDC4 gene function is required at G1/S and G2/M transitions during mitosis and at various stages during meiosis. (en)
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| dbo:entrezgene
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| dbo:symbol
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- Cdc4
- Egg laying defective protein 41
- F-box/WD repeat-containing protein sel-10
- Fbw7
- Suppressor/enhancer of lin-12 protein 10
- cell division control protein 4
- F-box and WD-40 domain-containing protein 7, F-box protein FBX30, Archipelago homolog (hAgo), SEL-10, hCdc4
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| dbo:thumbnail
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| dbo:uniprot
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| dbo:wikiPageID
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| dbo:wikiPageLength
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- 15947 (xsd:nonNegativeInteger)
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| dbo:wikiPageRevisionID
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| dbo:wikiPageWikiLink
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| dbp:altsymbols
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- cell division control protein 4 (en)
- F-box and WD-40 domain-containing protein 7, F-box protein FBX30, Archipelago homolog , SEL-10, hCdc4 (en)
- Suppressor/enhancer of lin-12 protein 10
Egg laying defective protein 41 (en)
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| dbp:caption
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- Crystal structure of Cdc4 (en)
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| dbp:entrezgene
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| dbp:name
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- Cdc4 (en)
- F-box/WD repeat-containing protein 7 (en)
- F-box/WD repeat-containing protein sel-10 (en)
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| dbp:symbol
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- Cdc4 (en)
- F-box/WD repeat-containing protein sel-10 (en)
- Fbw7 (en)
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| dbp:uniprot
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- P07834 (en)
- Q93794 (en)
- Q969H0 (en)
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| dbp:wikiPageUsesTemplate
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| dcterms:subject
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| gold:hypernym
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| rdf:type
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| rdfs:comment
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- Cdc4 (cell division control protein 4) is a substrate recognition component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which acts as a mediator of ubiquitin transfer to target proteins, leading to their subsequent degradation via the ubiquitin-proteasome pathway. Cdc4 targets primarily cell cycle regulators for proteolysis. It serves the function of an adaptor that brings target molecules to the core SCF complex. Cdc4 was originally identified in the model organism Saccharomyces cerevisiae. CDC4 gene function is required at G1/S and G2/M transitions during mitosis and at various stages during meiosis. (en)
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| rdfs:label
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- Cell division control protein 4 (en)
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| owl:sameAs
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| prov:wasDerivedFrom
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| foaf:depiction
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| foaf:isPrimaryTopicOf
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| foaf:name
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- Cdc4 (en)
- F-box/WD repeat-containing protein 7 (en)
- F-box/WD repeat-containing protein sel-10 (en)
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| is dbo:wikiPageWikiLink
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| is foaf:primaryTopic
of | |
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