The Canadian National Breast Screening Study, sometimes abbreviated as CNBSS or NBSS, was a randomized trial conducted with the aim of evaluating whether mammography reduced breast cancer incidence or mortality among women who underwent screening. The trial was initiated in 1980, and was conducted in fifteen screening centers in six different Canadian provinces. It was the first study designed to determine whether mammography was effective among women between the ages of 40 and 49.
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