About: CX157

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA). As of 2007 it was in phase II clinical trials for the treatment of depression. In 2013, work on the drug was terminated.[1]

Property	Value
dbo:abstract	CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA). As of 2007 it was in phase II clinical trials for the treatment of depression. In 2013, work on the drug was terminated.[1] (en)
dbo:casNumber	205187-53-7
dbo:fdaUniiCode	O6L62LZJ0Q
dbo:pubchem	18687754
dbo:thumbnail	wiki-commons:Special:FilePath/CX157_structure.svg?width=300
dbo:wikiPageExternalLink	http://adisinsight.springer.com/drugs/800025697
dbo:wikiPageID	23042014 (xsd:integer)
dbo:wikiPageLength	2470 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1120071400 (xsd:integer)
dbo:wikiPageWikiLink	dbc:Sulfones dbc:Reversible_inhibitors_of_MAO-A dbr:Reversible_inhibitor_of_monoamine_oxidase_A dbc:Abandoned_drugs dbc:Fluoroarenes dbc:Sulfur_heterocycles dbc:Trifluoromethyl_compounds dbr:Clinical_depression dbr:Clinical_trial dbc:Monoamine_oxidase_inhibitors dbr:Binding_selectivity dbr:Phases_of_clinical_research
dbp:atcPrefix	none (en)
dbp:c	14 (xsd:integer)
dbp:casNumber	205187 (xsd:integer)
dbp:chemspiderid	13701383 (xsd:integer)
dbp:f	4 (xsd:integer)
dbp:h	8 (xsd:integer)
dbp:iupacName	3 (xsd:integer)
dbp:legalStatus	Uncontrolled (en)
dbp:o	4 (xsd:integer)
dbp:pubchem	18687754 (xsd:integer)
dbp:routesOfAdministration	Oral (en)
dbp:s	1 (xsd:integer)
dbp:smiles	FCCOc2cc3Oc1ccccc1Sc3cc2 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	PDIMOTRDGUQMNY-UHFFFAOYSA-N (en)
dbp:unii	O6L62LZJ0Q (en)
dbp:verifiedrevid	396516252 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Drugbox dbt:Nervous-system-drug-stub dbt:Reflist dbt:Short_description dbt:Cascite dbt:Chemspidercite dbt:Fdacite dbt:Stdinchicite dbt:Monoamine_metabolism_modulators
dcterms:subject	dbc:Sulfones dbc:Reversible_inhibitors_of_MAO-A dbc:Abandoned_drugs dbc:Fluoroarenes dbc:Sulfur_heterocycles dbc:Trifluoromethyl_compounds dbc:Monoamine_oxidase_inhibitors
gold:hypernym	dbr:Inhibitor
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatMonoamineOxidaseInhibitors yago:Agent114778436 yago:Antidepressant102718811 yago:CausalAgent100007347 yago:Drug103247620 yago:Matter100020827 yago:Medicine103740161 yago:MonoamineOxidaseInhibitor103783017 yago:PhysicalEntity100001930 dbo:Drug yago:Substance100020090
rdfs:comment	CX157 (proposed trade name TriRima, formerly Tyrima) is a selective and reversible inhibitor of MAO-A (RIMA). As of 2007 it was in phase II clinical trials for the treatment of depression. In 2013, work on the drug was terminated.[1] (en)
rdfs:label	CX157 (en)
owl:sameAs	freebase:CX157 yago-res:CX157 wikidata:CX157 dbpedia-sh:CX157 dbpedia-sr:CX157 https://global.dbpedia.org/id/4e77V
prov:wasDerivedFrom	wikipedia-en:CX157?oldid=1120071400&ns=0
foaf:depiction	wiki-commons:Special:FilePath/CX157_structure.svg
foaf:isPrimaryTopicOf	wikipedia-en:CX157
is dbo:wikiPageRedirects of	dbr:C14H8F4O4S dbr:Tyrima
is dbo:wikiPageWikiLink of	dbr:Monoamine_oxidase_inhibitor dbr:C14H8F4O4S dbr:Tyrima
is foaf:primaryTopic of	wikipedia-en:CX157