| dbo:abstract
|
- COS are fibroblast-like cell lines derived from monkey kidney tissue. COS cells are obtained by immortalizing CV-1 cells with a version of the SV40 virus that can produce large T antigen but has a defect in genomic replication. The CV-1 cell line in turn was derived from the kidney of the African green monkey. The acronym "COS" is derived from the cells being CV-1 (simian) in Origin, and carrying the SV40 genetic material. Three COS lines were created (COS-1, COS-3 and COS-7), of which two are commonly used (COS-1 and COS-7). (en)
- COS-Zellen (von engl. CV-1 in Origin, carrying SV40 ‚ursprünglich CV-1, trägt SV40‘) sind Zellen einer Zelllinie, die aus den immortalisierten einer afrikanischen grünen Meerkatze (Chlorocebus aethiops) durch Transformation mit einem replikationsdefizienten Simian-Virus 40 hervorgegangen sind. Sie werden unter anderem zur Herstellung rekombinanter Proteine und zur Kultur mancher Viren verwendet. (de)
- COS-7 (亦稱ATCC CRL-1651、CV-1 in Origin Simian-7) 是在1980年代初期發現的非洲綠猴腎細胞系，最初是經帶有編碼野生型T抗原的起始失活突變的猿猴空泡病毒40轉染而建立，具有成纖維細胞樣和病毒敏感性的獨特特徵。穩定的細胞系是轉運體相互作用研究及體外評價藥物候選物的理想模型，其中常用的其中一個宿主細胞系就是COS-7細胞。COS-7細胞也會應用在細胞基因轉錄的研究及DNA質體轉染實驗，從而分析類固醇生成基因、類固醇受體的功能及類固醇對功能分子的作用。COS-7是源自非類固醇生成器官的非類固醇生成細胞，然而有研究表明COS-7細胞可將3H-睪酮代謝為3H-雄烯二酮。 (zh)
- COS是衍生自猴腎組織的成纖維細胞樣細胞系，常用於科研用途。 (zh)
|
| dbo:thumbnail
| |
| dbo:wikiPageExternalLink
| |
| dbo:wikiPageID
| |
| dbo:wikiPageLength
|
- 3054 (xsd:nonNegativeInteger)
|
| dbo:wikiPageRevisionID
| |
| dbo:wikiPageWikiLink
| |
| dbp:wikiPageUsesTemplate
| |
| dcterms:subject
| |
| gold:hypernym
| |
| rdf:type
| |
| rdfs:comment
|
- COS are fibroblast-like cell lines derived from monkey kidney tissue. COS cells are obtained by immortalizing CV-1 cells with a version of the SV40 virus that can produce large T antigen but has a defect in genomic replication. The CV-1 cell line in turn was derived from the kidney of the African green monkey. The acronym "COS" is derived from the cells being CV-1 (simian) in Origin, and carrying the SV40 genetic material. Three COS lines were created (COS-1, COS-3 and COS-7), of which two are commonly used (COS-1 and COS-7). (en)
- COS-Zellen (von engl. CV-1 in Origin, carrying SV40 ‚ursprünglich CV-1, trägt SV40‘) sind Zellen einer Zelllinie, die aus den immortalisierten einer afrikanischen grünen Meerkatze (Chlorocebus aethiops) durch Transformation mit einem replikationsdefizienten Simian-Virus 40 hervorgegangen sind. Sie werden unter anderem zur Herstellung rekombinanter Proteine und zur Kultur mancher Viren verwendet. (de)
- COS-7 (亦稱ATCC CRL-1651、CV-1 in Origin Simian-7) 是在1980年代初期發現的非洲綠猴腎細胞系，最初是經帶有編碼野生型T抗原的起始失活突變的猿猴空泡病毒40轉染而建立，具有成纖維細胞樣和病毒敏感性的獨特特徵。穩定的細胞系是轉運體相互作用研究及體外評價藥物候選物的理想模型，其中常用的其中一個宿主細胞系就是COS-7細胞。COS-7細胞也會應用在細胞基因轉錄的研究及DNA質體轉染實驗，從而分析類固醇生成基因、類固醇受體的功能及類固醇對功能分子的作用。COS-7是源自非類固醇生成器官的非類固醇生成細胞，然而有研究表明COS-7細胞可將3H-睪酮代謝為3H-雄烯二酮。 (zh)
- COS是衍生自猴腎組織的成纖維細胞樣細胞系，常用於科研用途。 (zh)
|
| rdfs:label
|
- COS-Zellen (de)
- COS cells (en)
- COS-7 (zh)
- COS細胞 (zh)
|
| owl:sameAs
| |
| prov:wasDerivedFrom
| |
| foaf:depiction
| |
| foaf:isPrimaryTopicOf
| |
| is dbo:wikiPageDisambiguates
of | |
| is dbo:wikiPageRedirects
of | |
| is dbo:wikiPageWikiLink
of | |
| is foaf:primaryTopic
of | |
