About: MK-2206

An Entity of Type: person, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

MK-2206 is a drug candidate being investigated to help treat cancer. Its chemical formula is C25H21N5O. It acts as an allosteric AKT inhibitor. It is a highly selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3. It is intended to be used with other cancer therapies that advanced tumours may become resistant to.

Property	Value
dbo:abstract	MK-2206 is a drug candidate being investigated to help treat cancer. Its chemical formula is C25H21N5O. It acts as an allosteric AKT inhibitor. It is a highly selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3. It is intended to be used with other cancer therapies that advanced tumours may become resistant to. (en)
dbo:iupacName	8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one (en)
dbo:thumbnail	wiki-commons:Special:FilePath/MK-2206.svg?width=300
dbo:wikiPageID	48532500 (xsd:integer)
dbo:wikiPageLength	4907 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1033917947 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Breast_cancer dbr:In_vitro dbc:Amines dbc:Heterocyclic_compounds_with_3_rings dbc:Nitrogen_heterocycles dbr:SARS-CoV-2 dbc:Experimental_cancer_drugs dbr:Clinical_trial dbr:Allosteric dbr:Preprint dbc:Cyclobutanes dbr:Adaptive_clinical_trial dbc:Protein_kinase_inhibitors dbr:Autophagy dbr:I-SPY2 dbr:Akt1 dbr:Akt2 dbr:Akt3 dbr:AKT_inhibitor
dbp:imagefile	MK-2206.svg (en)
dbp:imagesize	200 (xsd:integer)
dbp:pin	8 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Antineoplastic-drug-stub dbt:As_of dbt:Chembox dbt:Chembox_Hazards dbt:Chembox_Identifiers dbt:Chembox_Properties dbt:Reflist dbt:Cascite
dcterms:subject	dbc:Amines dbc:Heterocyclic_compounds_with_3_rings dbc:Nitrogen_heterocycles dbc:Experimental_cancer_drugs dbc:Cyclobutanes dbc:Protein_kinase_inhibitors
gold:hypernym	dbr:Candidate
rdf:type	owl:Thing dbo:Person dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q11173 dbo:ChemicalCompound
rdfs:comment	MK-2206 is a drug candidate being investigated to help treat cancer. Its chemical formula is C25H21N5O. It acts as an allosteric AKT inhibitor. It is a highly selective inhibitor of pan-Akt, namely, of all three Akt isoforms Akt1, Akt2, and Akt3. It is intended to be used with other cancer therapies that advanced tumours may become resistant to. (en)
rdfs:label	MK-2206 (en)
owl:sameAs	yago-res:MK-2206 wikidata:MK-2206 https://global.dbpedia.org/id/2Mnga
prov:wasDerivedFrom	wikipedia-en:MK-2206?oldid=1033917947&ns=0
foaf:depiction	wiki-commons:Special:FilePath/MK-2206.svg
foaf:isPrimaryTopicOf	wikipedia-en:MK-2206
is dbo:wikiPageRedirects of	dbr:C25H21N5O
is dbo:wikiPageWikiLink of	dbr:Protein_kinase_B dbr:C25H21N5O
is foaf:primaryTopic of	wikipedia-en:MK-2206