About: Btz domain

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

In molecular biology, the Btz domain (CASC3/Barentsz eIF4AIII binding domain) is a protein domain found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional regulation of mRNA in metazoa. The complex is formed by the association of four proteins (eIF4AIII, Barentsz, Mago, and Y14), mRNA, and ATP. This domain wraps around eIF4AIII and stacks against the 5' nucleotide.

Property	Value
dbo:abstract	In molecular biology, the Btz domain (CASC3/Barentsz eIF4AIII binding domain) is a protein domain found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional regulation of mRNA in metazoa. The complex is formed by the association of four proteins (eIF4AIII, Barentsz, Mago, and Y14), mRNA, and ATP. This domain wraps around eIF4AIII and stacks against the 5' nucleotide. (en)
dbo:symbol	Btz
dbo:thumbnail	wiki-commons:Special:FilePath/PDB_2hyi_EBI.jpg?width=300
dbo:wikiPageID	32171973 (xsd:integer)
dbo:wikiPageLength	1926 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	995781543 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Nucleotide dbr:CASC3 dbr:Post-transcriptional_regulation dbr:Directionality_(molecular_biology) dbr:Protein_complex dbr:Protein_domain dbr:Protein dbr:Regulation dbc:Protein_domains dbr:EIF4A3 dbr:MAGOH dbr:Metazoa dbr:Exon_junction_complex dbr:RBM8A
dbp:caption	structure of the human exon junction complex with a trapped dead-box helicase bound to rna (en)
dbp:interpro	IPR018545 (en)
dbp:name	Btz (en)
dbp:pfam	PF09405 (en)
dbp:symbol	Btz (en)
dbp:wikiPageUsesTemplate	dbt:Infobox_protein_family dbt:InterPro_content dbt:Reflist
dcterms:subject	dbc:Protein_domains
gold:hypernym	dbr:Domain
rdf:type	owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:Abstraction100002137 yago:Family108078020 yago:Group100031264 yago:Organization108008335 yago:YagoLegalActor yago:YagoLegalActorGeo yago:YagoPermanentlyLocatedEntity dbo:Protein yago:SocialGroup107950920 yago:Unit108189659
rdfs:comment	In molecular biology, the Btz domain (CASC3/Barentsz eIF4AIII binding domain) is a protein domain found on CASC3 (cancer susceptibility candidate gene 3 protein) which is also known as Barentsz (Btz). CASC3 is a component of the EJC (exon junction complex) which is a complex that is involved in post-transcriptional regulation of mRNA in metazoa. The complex is formed by the association of four proteins (eIF4AIII, Barentsz, Mago, and Y14), mRNA, and ATP. This domain wraps around eIF4AIII and stacks against the 5' nucleotide. (en)
rdfs:label	Btz domain (en)
owl:sameAs	freebase:Btz domain wikidata:Btz domain https://global.dbpedia.org/id/2L435
prov:wasDerivedFrom	wikipedia-en:Btz_domain?oldid=995781543&ns=0
foaf:depiction	wiki-commons:Special:FilePath/PDB_2hyi_EBI.jpg
foaf:isPrimaryTopicOf	wikipedia-en:Btz_domain
is foaf:primaryTopic of	wikipedia-en:Btz_domain