About: Bacterial initiation factor 2

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Bacterial initiation factor-2 is a bacterial initiation factor. IF2 binds to an initiator tRNA and controls the entry of tRNA onto the ribosome. IF2, bound to GTP, binds to the 30S P site. After associating with the 30S subunit, fMet-tRNAf binds to the IF2 then IF2 transfers the tRNA into the partial P site. When the 50S subunit joins, it hydrolyzes GTP to GDP and Pi, causing a conformational change in the IF2 that causes IF2 to release and allow the 70S ribosome to form. Human mitochondria use a nuclear-encoded homolog, MTIF2, for translation initiation.

Property Value
dbo:abstract
  • Bacterial initiation factor-2 is a bacterial initiation factor. IF2 binds to an initiator tRNA and controls the entry of tRNA onto the ribosome. IF2, bound to GTP, binds to the 30S P site. After associating with the 30S subunit, fMet-tRNAf binds to the IF2 then IF2 transfers the tRNA into the partial P site. When the 50S subunit joins, it hydrolyzes GTP to GDP and Pi, causing a conformational change in the IF2 that causes IF2 to release and allow the 70S ribosome to form. Human mitochondria use a nuclear-encoded homolog, MTIF2, for translation initiation. (en)
dbo:wikiPageID
  • 21932809 (xsd:integer)
dbo:wikiPageLength
  • 1307 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 951715200 (xsd:integer)
dbo:wikiPageWikiLink
dbp:interpro
  • IPR000178 (en)
dbp:name
  • Translation initiation factor IF-2, bacterial-like (en)
dbp:wikiPageUsesTemplate
dcterms:subject
rdf:type
rdfs:comment
  • Bacterial initiation factor-2 is a bacterial initiation factor. IF2 binds to an initiator tRNA and controls the entry of tRNA onto the ribosome. IF2, bound to GTP, binds to the 30S P site. After associating with the 30S subunit, fMet-tRNAf binds to the IF2 then IF2 transfers the tRNA into the partial P site. When the 50S subunit joins, it hydrolyzes GTP to GDP and Pi, causing a conformational change in the IF2 that causes IF2 to release and allow the 70S ribosome to form. Human mitochondria use a nuclear-encoded homolog, MTIF2, for translation initiation. (en)
rdfs:label
  • Bacterial initiation factor 2 (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageDisambiguates of
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License