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- Brivanib alaninate (INN/USAN) also known as BMS-582664 is an investigational, anti-tumorigenic drug for oral administration. The drug is being developed by Bristol-Myers Squibb for the treatment of hepatocellular carcinoma or HCC (also called malignant hepatoma), the most common type of liver cancer. Brivanib is no longer in active development. Brivanib alaninate is a multitargeted tyrosine kinase inhibitor (as is sorafenib). Brivanib alaninate also inhibits VEGFR and fibroblast growth factor receptors (FGFR), which is known to play a major role in the etiopathogenesis of HCC. To date, brivanib alaninate has been investigated in 29 studies, including more than 4,000 patients around the world. (en)
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- 11987 (xsd:nonNegativeInteger)
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- --1-propan-2-yl 2-aminopropanoate (en)
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- CC1=CC2=CC=CCOC3=NC=NN4C3=CC (en)
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- LTEJRLHKIYCEOX-OCCSQVGLSA-N (en)
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- Brivanib alaninate (INN/USAN) also known as BMS-582664 is an investigational, anti-tumorigenic drug for oral administration. The drug is being developed by Bristol-Myers Squibb for the treatment of hepatocellular carcinoma or HCC (also called malignant hepatoma), the most common type of liver cancer. Brivanib is no longer in active development. Brivanib alaninate is a multitargeted tyrosine kinase inhibitor (as is sorafenib). (en)
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