About: BL-1020

Property	Value
dbo:abstract	BL-1020 (perphenazine 4-aminobutanoate) is an investigational orally-active antipsychotic for the possible treatment of schizophrenia. The chemical is an ester of GABA and perphenazine; pharmacologically it acts as a D2 antagonist and GABA agonist. It has shown pro-cognitive effects in the trials. In March 2013, it went into the II/III trial phase. It has been introduced by BioLineRx, a biopharmaceutical development company. (en) Le BL-1020 (4-aminobutanoate de perphenazine) est un antipsychotique. Il s'agit d'un ester de la perphénazine et du GABA, présentant moins d'effet indésirables que cette dernière ainsi que des effets pro-cognitifs dans les essais. Il a été développé par , une société pharmaceutique israélienne. (fr)
dbo:casNumber	751477-01-7
dbo:chEMBL	1187646
dbo:fdaUniiCode	K1WO7H97QZ
dbo:pubchem	11203271
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dbp:casNumber	751477 (xsd:integer)
dbp:chembl	1187646 (xsd:integer)
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dbp:pubchem	11203271 (xsd:integer)
dbp:s	1 (xsd:integer)
dbp:smiles	C1CNCCOCCCCN (en)
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dbp:stdinchikey	BABFYCSPNDKXRI-UHFFFAOYSA-N (en)
dbp:unii	K1WO7H97QZ (en)
dbp:width	250 (xsd:integer)
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dcterms:subject	dbc:Chloroarenes dbc:Piperazines dbc:5-HT2A_antagonists dbc:Antipsychotics dbc:D2_antagonists dbc:GABA_receptor_agonists
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatAntipsychotics yago:Agent114778436 yago:CausalAgent100007347 yago:Drug103247620 yago:DrugOfAbuse103248958 yago:MajorTranquilizer103713736 yago:Matter100020827 yago:Medicine103740161 yago:PhysicalEntity100001930 yago:PsychotropicAgent104017429 dbo:Drug yago:Sedative-hypnotic104166841 yago:Sedative104166553 yago:Substance100020090 yago:Tranquilizer104470232
rdfs:comment	BL-1020 (perphenazine 4-aminobutanoate) is an investigational orally-active antipsychotic for the possible treatment of schizophrenia. The chemical is an ester of GABA and perphenazine; pharmacologically it acts as a D2 antagonist and GABA agonist. It has shown pro-cognitive effects in the trials. In March 2013, it went into the II/III trial phase. It has been introduced by BioLineRx, a biopharmaceutical development company. (en) Le BL-1020 (4-aminobutanoate de perphenazine) est un antipsychotique. Il s'agit d'un ester de la perphénazine et du GABA, présentant moins d'effet indésirables que cette dernière ainsi que des effets pro-cognitifs dans les essais. Il a été développé par , une société pharmaceutique israélienne. (fr)
rdfs:label	BL-1020 (en) BL 1020 (fr)
owl:sameAs	freebase:BL-1020 yago-res:BL-1020 wikidata:BL-1020 dbpedia-fr:BL-1020 https://global.dbpedia.org/id/2Yof1
prov:wasDerivedFrom	wikipedia-en:BL-1020?oldid=1120071972&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Perphenazine_gamma-aminobutyrate.svg
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