About: Atiprimod

An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Atiprimod (INN, codenamed SK&F106615) is a substance being studied in the treatment of certain multiple myelomas and other advanced cancers. It may block the growth of tumors and the growth of blood vessels from surrounding tissue to the tumor. This drug is also being researched as a potential treatment for various autoimmune diseases. It was first developed by GlaxoSmithKline as a potential treatment for rheumatoid arthritis. The substance is also known as azaspirane, although this more properly refers to the class of chemicals to which atiprimod belongs.

Property	Value
dbo:abstract	Atiprimod (INN, codenamed SK&F106615) is a substance being studied in the treatment of certain multiple myelomas and other advanced cancers. It may block the growth of tumors and the growth of blood vessels from surrounding tissue to the tumor. This drug is also being researched as a potential treatment for various autoimmune diseases. It was first developed by GlaxoSmithKline as a potential treatment for rheumatoid arthritis. The substance is also known as azaspirane, although this more properly refers to the class of chemicals to which atiprimod belongs. This compound has also been shown to kill mantle cell lymphoma cells in vitro. (en)
dbo:casNumber	123018-47-3
dbo:chEMBL	103735
dbo:fdaUniiCode	MG7D3QD743
dbo:kegg	D03003
dbo:pubchem	129869
dbo:thumbnail	wiki-commons:Special:FilePath/Atiprimod.svg?width=300
dbo:wikiPageExternalLink	http://www.cancer.gov/dictionary%3FCdrID=486451
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dbo:wikiPageRevisionID	1084691994 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Cancer dbr:Blood_vessels dbr:Rheumatoid_arthritis dbr:In_vitro dbc:Pyrrolidines dbc:Spiro_compounds dbr:Vascular_endothelial_growth_factor dbr:GlaxoSmithKline dbr:Multiple_myeloma dbc:Experimental_cancer_drugs dbr:Amphiphilic dbr:Cation dbr:Tumor dbr:Angiogenesis dbr:PH dbc:Diethylamino_compounds dbr:International_Nonproprietary_Name dbr:Blood_(journal) dbr:Mantle_cell_lymphoma dbr:Autoimmune_diseases dbr:File:Atiprimod.png
dbp:alt	Ball-and-stick model of the atiprimod molecule (en)
dbp:atcPrefix	none (en)
dbp:c	22 (xsd:integer)
dbp:casNumber	123018 (xsd:integer)
dbp:chembl	103735 (xsd:integer)
dbp:chemspiderid	114962 (xsd:integer)
dbp:h	44 (xsd:integer)
dbp:image	Atiprimod molecule ball.png (en)
dbp:iupacName	3 (xsd:integer)
dbp:kegg	D03003 (en)
dbp:n	2 (xsd:integer)
dbp:pubchem	129869 (xsd:integer)
dbp:smiles	NCCCN2CCC1C2 (en)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	SERHTTSLBVGRBY-UHFFFAOYSA-N (en)
dbp:unii	MG7D3QD743 (en)
dbp:verifiedfields	changed (en)
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dbp:width	250 (xsd:integer)
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dcterms:subject	dbc:Pyrrolidines dbc:Spiro_compounds dbc:Experimental_cancer_drugs dbc:Diethylamino_compounds
gold:hypernym	dbr:Substance
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatMolecularFormulas yago:WikicatSpiroCompounds yago:Abstraction100002137 yago:Cognition100023271 yago:Communication100033020 yago:Compound105870180 yago:Concept105835747 yago:Content105809192 yago:Formula106816935 yago:Idea105833840 yago:Message106598915 yago:MolecularFormula106817173 yago:PsychologicalFeature100023100 dbo:ChemicalCompound dbo:Drug yago:Statement106722453 yago:Whole105869584 umbel-rc:DrugProduct
rdfs:comment	Atiprimod (INN, codenamed SK&F106615) is a substance being studied in the treatment of certain multiple myelomas and other advanced cancers. It may block the growth of tumors and the growth of blood vessels from surrounding tissue to the tumor. This drug is also being researched as a potential treatment for various autoimmune diseases. It was first developed by GlaxoSmithKline as a potential treatment for rheumatoid arthritis. The substance is also known as azaspirane, although this more properly refers to the class of chemicals to which atiprimod belongs. (en)
rdfs:label	Atiprimod (en)
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