He was born in Scanno in the region of the Abruzzo, but then belonging to the kingdom of Naples. He was born to a well-to-do family invested in herding animals. He initially studied under the Jesuits in Chieti, but moved to Naples in 1757. He was well versed in the classic languages. He would divide much of his life between Scanno and Naples. Returning in 1761 to Naples, he was accepted as a member of the Royal Academy of Sciences. He published on diverse subjects, sometimes anonymously, and often to dispute a prior thesis.
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