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In enzymology, an aminodeoxychorismate synthase (EC 2.6.1.85) is an enzyme that catalyzes the chemical reaction chorismate + L-glutamine 4-amino-4-deoxychorismate + L-glutamate Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its two products are and L-glutamate. Aminodeoxychorismate synthase (PabB), a 51 kDa protein in E. coli, is encoded by the gene pabB. 4-amino-4-deoxychorismate, the product of PabB, can be converted to para-aminobenzoic acid by the enzyme 4-amino-4-deoxychorismate lyase (PabC).

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dbo:abstract
  • In enzymology, an aminodeoxychorismate synthase (EC 2.6.1.85) is an enzyme that catalyzes the chemical reaction chorismate + L-glutamine 4-amino-4-deoxychorismate + L-glutamate Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its two products are and L-glutamate. It is part of a pathway for the biosynthesis of para-aminobenzoic acid (PABA); a precursor for the production of folates. Folates are family of cofactors that are essential for living organisms. Folate cofactors are used in several one-carbon transfer reactions required during the synthesis of essential metabolites, including methionine and thymidylate. Aminodeoxychorismate synthase (PabB), a 51 kDa protein in E. coli, is encoded by the gene pabB. 4-amino-4-deoxychorismate, the product of PabB, can be converted to para-aminobenzoic acid by the enzyme 4-amino-4-deoxychorismate lyase (PabC). (en)
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  • 2.6.1.85
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  • Aminodeoxychorismate synthase (en)
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  • 132264 (xsd:integer)
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  • 2.600000 (xsd:double)
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  • 46820 (xsd:integer)
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  • In enzymology, an aminodeoxychorismate synthase (EC 2.6.1.85) is an enzyme that catalyzes the chemical reaction chorismate + L-glutamine 4-amino-4-deoxychorismate + L-glutamate Thus, the two substrates of this enzyme are chorismate and L-glutamine, whereas its two products are and L-glutamate. Aminodeoxychorismate synthase (PabB), a 51 kDa protein in E. coli, is encoded by the gene pabB. 4-amino-4-deoxychorismate, the product of PabB, can be converted to para-aminobenzoic acid by the enzyme 4-amino-4-deoxychorismate lyase (PabC). (en)
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  • Aminodeoxychorismate synthase (en)
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  • 4-amino-4-deoxychorismate synthase (en)
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