An Entity of Type: chemical substance, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp. It is the α epimer of β-zearalenol and along with β-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism. A relatively low proportion of β-zearalenol is formed from zearalenone compared to α-zearalenol in humans. α-Zearalenol is about 3- to 4-fold more potent as an estrogen relative to zearalenone.

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dbo:abstract
  • α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp. It is the α epimer of β-zearalenol and along with β-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism. A relatively low proportion of β-zearalenol is formed from zearalenone compared to α-zearalenol in humans. α-Zearalenol is about 3- to 4-fold more potent as an estrogen relative to zearalenone. (en)
  • α-玉米赤霉烯醇是一个屬於与有關的的,出現於镰孢菌。它是β-玉米赤霉烯醇的α差向异构体,和β-玉米赤霉烯醇是玉米赤霉烯酮的一个主要代谢物,主要在肝脏中形成,但肠中進行首过代谢時也會形成少量。与人体内的α-玉米赤霉烯醇相比,有较少量的β-玉米赤霉烯醇是由玉米赤霉烯酮形成的。α-玉米赤霉烯醇的雌激素效力是玉米赤霉烯酮的三至四倍。 (zh)
dbo:casNumber
  • 36455-72-8
dbo:chEBI
  • 35065
dbo:chEMBL
  • 371463
dbo:fdaUniiCode
  • 59D4EVJ5KC
dbo:kegg
  • C14750
dbo:pubchem
  • 5284645
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  • 18 (xsd:integer)
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  • 36455 (xsd:integer)
dbp:chebi
  • 35065 (xsd:integer)
dbp:chembl
  • 371463 (xsd:integer)
dbp:chemspiderid
  • 4447689 (xsd:integer)
dbp:drugName
  • α-Zearalenol (en)
dbp:h
  • 24 (xsd:integer)
dbp:iupacName
  • -71517 (xsd:integer)
dbp:kegg
  • 14750.0
dbp:o
  • 5 (xsd:integer)
dbp:pubchem
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dbp:smiles
  • C[C@H]1CCC[C@@H]O (en)
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  • 1 (xsd:integer)
dbp:stdinchikey
  • FPQFYIAXQDXNOR-QDKLYSGJSA-N (en)
dbp:synonyms
  • alpha-Zearalenol; trans-Zearalenol; 2,4-Dihydroxy-6-benzoic acid μ-lactone (en)
dbp:unii
  • 59 (xsd:integer)
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rdfs:comment
  • α-Zearalenol is a nonsteroidal estrogen of the resorcylic acid lactone group related to mycoestrogens found in Fusarium spp. It is the α epimer of β-zearalenol and along with β-zearalenol is a major metabolite of zearalenone formed mainly in the liver but also to a lesser extent in the intestines during first-pass metabolism. A relatively low proportion of β-zearalenol is formed from zearalenone compared to α-zearalenol in humans. α-Zearalenol is about 3- to 4-fold more potent as an estrogen relative to zearalenone. (en)
  • α-玉米赤霉烯醇是一个屬於与有關的的,出現於镰孢菌。它是β-玉米赤霉烯醇的α差向异构体,和β-玉米赤霉烯醇是玉米赤霉烯酮的一个主要代谢物,主要在肝脏中形成,但肠中進行首过代谢時也會形成少量。与人体内的α-玉米赤霉烯醇相比,有较少量的β-玉米赤霉烯醇是由玉米赤霉烯酮形成的。α-玉米赤霉烯醇的雌激素效力是玉米赤霉烯酮的三至四倍。 (zh)
rdfs:label
  • Alpha-Zearalenol (en)
  • Α-玉米赤霉烯醇 (zh)
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  • α-Zearalenol (en)
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