About: Achaete-scute complex

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

The achaete-scute complex (AS-C) is a group of four genes (achaete, scute, lethal of scute, and asense) in the fruit fly Drosophila melanogaster. These genes encode basic helix-loop-helix transcription factors that have been best studied in their regulation of nervous system development. Because of their role in specifying neuroblast fate, the genes of the AS-C are called proneural genes. However, the AS-C has non-proneural functions, such as specifying muscle and gut progenitors. Homologues of AS-C in other animals, including humans and other vertebrates, have similar functions.

Property Value
dbo:abstract
  • The achaete-scute complex (AS-C) is a group of four genes (achaete, scute, lethal of scute, and asense) in the fruit fly Drosophila melanogaster. These genes encode basic helix-loop-helix transcription factors that have been best studied in their regulation of nervous system development. Because of their role in specifying neuroblast fate, the genes of the AS-C are called proneural genes. However, the AS-C has non-proneural functions, such as specifying muscle and gut progenitors. Homologues of AS-C in other animals, including humans and other vertebrates, have similar functions. Genes of the AS-C interact with the Notch pathway in both their proneural functions as well as their specification of gut and muscle cells. (en)
dbo:symbol
  • MASH1/Ascl1a-like
dbo:wikiPageID
  • 25237396 (xsd:integer)
dbo:wikiPageLength
  • 4185 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID
  • 1075849800 (xsd:integer)
dbo:wikiPageWikiLink
dbp:interpro
  • IPR015660 (en)
dbp:name
  • Achaete-scute complex protein T3 (en)
  • Achaete-scute complex protein T4 (en)
  • Achaete-scute complex protein T5 (en)
  • Achaete-scute complex protein T8 (en)
  • Achaete-scute-related (en)
dbp:organism
  • Drosophila melanogaster (en)
dbp:symbol
  • sc (en)
  • ac (en)
  • MASH1/Ascl1a-like (en)
  • ase (en)
  • lsc (en)
dbp:uniprot
  • P09774 (en)
  • P09775 (en)
  • P10083 (en)
  • P10084 (en)
dbp:wikiPageUsesTemplate
dcterms:subject
gold:hypernym
rdf:type
rdfs:comment
  • The achaete-scute complex (AS-C) is a group of four genes (achaete, scute, lethal of scute, and asense) in the fruit fly Drosophila melanogaster. These genes encode basic helix-loop-helix transcription factors that have been best studied in their regulation of nervous system development. Because of their role in specifying neuroblast fate, the genes of the AS-C are called proneural genes. However, the AS-C has non-proneural functions, such as specifying muscle and gut progenitors. Homologues of AS-C in other animals, including humans and other vertebrates, have similar functions. (en)
rdfs:label
  • Achaete-scute complex (en)
owl:sameAs
prov:wasDerivedFrom
foaf:isPrimaryTopicOf
is dbo:wikiPageRedirects of
is dbo:wikiPageWikiLink of
is foaf:primaryTopic of
Powered by OpenLink Virtuoso    This material is Open Knowledge     W3C Semantic Web Technology     This material is Open Knowledge    Valid XHTML + RDFa
This content was extracted from Wikipedia and is licensed under the Creative Commons Attribution-ShareAlike 3.0 Unported License