About: Levomethadone

Property	Value
dbo:abstract	Levomethadone, sold under the brand name L-Polamidon among others, is a synthetic opioid analgesic and antitussive which is marketed in Europe and is used for pain management and in opioid maintenance therapy. In addition to being used as a pharmaceutical drug itself, levomethadone is the main therapeutic component of methadone. Levomethadone is used for narcotic maintenance in place of, or in some cases alongside as an alternative, to racemic methadone, owing to concern about the cardiotoxic and QT-prolonging action of racemic methadone being exclusively caused by the dextrorotatory enantiomer, dextromethadone. (en)
dbo:casNumber	(HCl) 125-58-6
dbo:chEBI	136003
dbo:chEMBL	159659
dbo:fdaUniiCode	6Y75Z4E8NS
dbo:kegg	D08121
dbo:pubchem	22267
dbo:thumbnail	wiki-commons:Special:FilePath/Levomethadone_structure.svg?width=300
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dbo:wikiPageLength	11713 (xsd:nonNegativeInteger)
dbo:wikiPageRevisionID	1113683821 (xsd:integer)
dbo:wikiPageWikiLink	dbr:Potency_(pharmacology) dbr:Enantiomer dbc:Antitussives dbr:Betäubungsmittelgesetz dbr:Pharmaceutical dbr:Intramuscular_injection dbr:Racemic_mixture dbr:Intravenous_injection dbc:Analgesics dbc:Dimethylamino_compounds dbc:Glycine_receptor_antagonists dbc:Ketones dbc:Mu-opioid_receptor_agonists dbc:NMDA_receptor_antagonists dbr:Competitive_inhibition dbr:Oral_administration dbr:Opioid_receptor dbc:Drug_rehabilitation dbc:Nicotinic_antagonists dbr:Single_Convention_on_Narcotic_Drugs dbr:Subcutaneous_injection dbr:Receptor_antagonist dbr:Pharmacodynamics dbr:Drug dbr:Analgesic dbr:Europe dbr:Noncompetitive_inhibition dbr:Generic_term dbc:Synthetic_opioids dbr:Hydrochloride dbr:Opioid_replacement_therapy dbr:Μ-opioid_receptor dbr:Binding_selectivity dbr:Dextromethadone dbr:Antitussive dbr:Methadone dbr:Narcotic dbr:Opioid dbr:Pain_management dbr:NMDA_receptor dbr:Intrathecal_injection dbr:Synthetic_compound dbr:QT_prolongation dbr:Dextrorotatory dbr:Cardiotoxic dbr:Α3β4-nicotinic_receptor
dbp:atcPrefix	N07 (en)
dbp:atcSuffix	BC05 (en)
dbp:bioavailability	High (en)
dbp:c	21 (xsd:integer)
dbp:casNumber	125 (xsd:integer)
dbp:chebi	136003 (xsd:integer)
dbp:chembl	159659 (xsd:integer)
dbp:chemspiderid	20904 (xsd:integer)
dbp:eliminationHalfLife	64800.0
dbp:h	27 (xsd:integer)
dbp:image	Levomethadone-xtal-1974-ball-and-stick.png (en)
dbp:iupacName	-6 (xsd:integer)
dbp:kegg	D08121 (en)
dbp:legalDe	Anlage III (en)
dbp:legalUk	Class A (en)
dbp:legalUn	Narcotic Schedule I (en)
dbp:legalUs	Schedule II (en)
dbp:meltingPoint	99.500000 (xsd:double)
dbp:n	1 (xsd:integer)
dbp:o	1 (xsd:integer)
dbp:proteinBound	60 (xsd:integer)
dbp:pubchem	22267 (xsd:integer)
dbp:routesOfAdministration	dbr:Intramuscular_injection dbr:Intravenous_injection dbr:Oral_administration dbr:Subcutaneous_injection dbr:Intrathecal_injection
dbp:smiles	O=CCC (en)
dbp:solubility	48.480000 (xsd:double)
dbp:stdinchi	1 (xsd:integer)
dbp:stdinchikey	USSIQXCVUWKGNF-QGZVFWFLSA-N (en)
dbp:synonyms	Levamethadone; l-Methadone; 6R-Methadone; -Methadone; R--Methadone; D--Methadone (en)
dbp:title	dbr:Pharmacodynamics
dbp:titlestyle	background:#ccccff (en)
dbp:unii	6 (xsd:integer)
dbp:width	200 (xsd:integer) 225 (xsd:integer)
dbp:wikiPageUsesTemplate	dbt:Analgesics dbt:CAS dbt:Clear dbt:Drugbox dbt:Glycine_receptor_modulators dbt:Ionotropic_glutamate_receptor_modulators dbt:Navboxes dbt:Reflist dbt:Short_description dbt:Abbrlink dbt:Fdacite dbt:Nicotinic_acetylcholine_receptor_modulators dbt:Opioid_receptor_modulators dbt:Antitussives dbt:Drugs.com dbt:Antiaddictives dbt:Methadone_at_opioid_receptors,_monoamine_transporters,_and_the_NMDA_receptor
dcterms:subject	dbc:Antitussives dbc:Analgesics dbc:Dimethylamino_compounds dbc:Glycine_receptor_antagonists dbc:Ketones dbc:Mu-opioid_receptor_agonists dbc:NMDA_receptor_antagonists dbc:Drug_rehabilitation dbc:Nicotinic_antagonists dbc:Synthetic_opioids
rdf:type	owl:Thing dul:ChemicalObject dbo:ChemicalSubstance wikidata:Q8386 yago:WikicatNMDAReceptorAntagonists yago:WikicatNicotinicAntagonists yago:Adversary109773245 yago:CausalAgent100007347 yago:LivingThing100004258 yago:Object100002684 yago:Organism100004475 yago:Person100007846 yago:PhysicalEntity100001930 yago:YagoLegalActor yago:YagoLegalActorGeo dbo:Drug yago:Whole100003553
rdfs:comment	Levomethadone, sold under the brand name L-Polamidon among others, is a synthetic opioid analgesic and antitussive which is marketed in Europe and is used for pain management and in opioid maintenance therapy. In addition to being used as a pharmaceutical drug itself, levomethadone is the main therapeutic component of methadone. (en)
rdfs:label	Levomethadone (en)
owl:sameAs	freebase:Levomethadone yago-res:Levomethadone wikidata:Levomethadone dbpedia-sh:Levomethadone dbpedia-sr:Levomethadone dbpedia-vi:Levomethadone https://global.dbpedia.org/id/4qD4h
prov:wasDerivedFrom	wikipedia-en:Levomethadone?oldid=1113683821&ns=0
foaf:depiction	wiki-commons:Special:FilePath/Levomethadone-xtal-1974-ball-and-stick.png wiki-commons:Special:FilePath/Levomethadone_structure.svg
foaf:isPrimaryTopicOf	wikipedia-en:Levomethadone
is dbo:wikiPageRedirects of	dbr:ATC_code_N07BC05 dbr:ATCvet_code_QN07BC05
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is foaf:primaryTopic of	wikipedia-en:Levomethadone