About: APC/C activator protein CDH1

An Entity of Type: protein, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Cdh1 (cdc20 homolog 1) is one of the substrate adaptor protein of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning as an activator of the APC/C, Cdh1 regulates the activity and substrate specificity of this ubiquitin E3-ligase. The human homolog is encoded by the FZR1 gene, which is not to be confused with the CDH1 gene.

Property	Value
dbo:abstract	Cdh1 (cdc20 homolog 1) is one of the substrate adaptor protein of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning as an activator of the APC/C, Cdh1 regulates the activity and substrate specificity of this ubiquitin E3-ligase. The human homolog is encoded by the FZR1 gene, which is not to be confused with the CDH1 gene. (en)
dbo:pdb	2ovq
dbo:symbol	Cdh1, Hct1
dbo:thumbnail	wiki-commons:Special:FilePath/SCF(Fbw7).png?width=300
dbo:uniprot	P53197
dbo:wikiPageExternalLink	http://swissmodel.expasy.org/%3Fpid=smr03&uid=&token=&query_1_input=P53197&mid=7d8f426e5859a8964ceb31d076c1fb2f_UP000011_33&zid=async https://web.archive.org/web/20110612192656/http:/www.yeastgenome.org/cgi-bin/locus.fpl%3Frm=display_result&dbid=S000002971
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dbo:wikiPageWikiLink	dbr:Cancer dbr:Proteasome dbr:FZR1_(gene) dbr:Structural_motif dbr:Cyclin-dependent_kinase dbr:Cyclin_A dbr:Cyclin_B dbr:Ubiquitin_ligase dbr:CDC20 dbr:CDC27 dbr:ETS2 dbr:Saccharomyces_cerevisiae dbr:Signal_transducing_adaptor_protein dbr:RNA_interference dbr:Anaphase-promoting_complex dbr:Proteolysis dbr:Aurora_B_kinase dbc:Proteins dbr:CDH1_(gene) dbr:Activator_(genetics) dbr:Cervical_cancer dbr:Threonine dbr:Tryptophan dbr:Tyrosine dbr:G1_phase dbr:Cyclins dbr:Telophase dbr:Amino_acid dbr:Cyclin dbr:Cytokinesis dbr:Drosophila dbr:Esophageal_cancer dbr:Cdc14 dbr:Cell_cycle dbr:Cell_division dbr:Cell_growth dbr:Chromosome_segregation dbr:Kinase dbr:Protein_domain dbr:Isoleucine dbr:Arginine dbr:Aspartic_acid dbc:Cell_cycle dbc:Saccharomyces_cerevisiae_genes dbr:Synapses dbr:Mitosis dbr:Axon dbr:C-terminus dbr:Serine dbr:S_phase dbr:Ubiquitin dbr:Cdc20 dbr:N-terminus dbr:Phosphorylation dbr:PLK1 dbr:Posttranslational_modification dbr:Enzyme_substrate dbr:Protein_degradation dbr:Cdc28 dbr:Cell-cycle dbr:E3_ubiquitin_ligase dbr:Beta_propeller dbr:WD_repeat dbr:File:SCF(Fbw7).PNG
dbp:name	SCF ubiquitin ligase complex (en)
dbp:pdb	2 (xsd:integer)
dbp:symbol	Cdh1, Hct1 (en)
dbp:uniprot	P53197 (en)
dbp:wikiPageUsesTemplate	dbt:Reflist dbt:Short_description dbt:Infobox_protein
dcterms:subject	dbc:Proteins dbc:Cell_cycle dbc:Saccharomyces_cerevisiae_genes
gold:hypernym	dbr:Protein
rdf:type	owl:Thing dbo:Biomolecule wikidata:Q206229 wikidata:Q8054 yago:WikicatSaccharomycesCerevisiaeGenes yago:Abstraction100002137 yago:Arrangement107938773 yago:Chemical114806838 yago:Compound114818238 yago:Gene105436752 yago:Group100031264 yago:Macromolecule114944888 yago:Material114580897 yago:Matter100020827 yago:Molecule114682133 yago:Ordering108456993 yago:OrganicCompound114727670 yago:Part113809207 yago:PhysicalEntity100001930 yago:Protein114728724 yago:Relation100031921 dbo:Protein yago:Sequence108459252 yago:Series108457976 yago:Substance100019613 yago:Thing100002452 yago:Unit109465459 yago:WikicatProteins
rdfs:comment	Cdh1 (cdc20 homolog 1) is one of the substrate adaptor protein of the anaphase-promoting complex (APC) in the budding yeast Saccharomyces cerevisiae. Functioning as an activator of the APC/C, Cdh1 regulates the activity and substrate specificity of this ubiquitin E3-ligase. The human homolog is encoded by the FZR1 gene, which is not to be confused with the CDH1 gene. (en)
rdfs:label	APC/C activator protein CDH1 (en)
owl:sameAs	freebase:APC/C activator protein CDH1 yago-res:APC/C activator protein CDH1 wikidata:APC/C activator protein CDH1 https://global.dbpedia.org/id/2ZqA5
prov:wasDerivedFrom	wikipedia-en:APC/C_activator_protein_CDH1?oldid=1122566960&ns=0
foaf:depiction	wiki-commons:Special:FilePath/SCF(Fbw7).png
foaf:isPrimaryTopicOf	wikipedia-en:APC/C_activator_protein_CDH1
foaf:name	SCF(Fbw7) ubiquitin ligase complex (en)
is dbo:wikiPageWikiLink of	dbr:Cadherin dbr:CDH1 dbr:Anaphase-promoting_complex dbr:Cadherin-1 dbr:Clb_5,6_(Cdk1) dbr:TPX2
is foaf:primaryTopic of	wikipedia-en:APC/C_activator_protein_CDH1