About: AB5 toxin

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The AB5 toxins are six-component protein complexes secreted by certain pathogenic bacteria known to cause human diseases such as cholera, dysentery, and hemolytic–uremic syndrome. One component is known as the A subunit, and the remaining five components are B subunits. All of these toxins share a similar structure and mechanism for entering targeted host cells. The B subunit is responsible for binding to receptors to open up a pathway for the A subunit to enter the cell. The A subunit is then able to use its catalytic machinery to take over the host cell's regular functions.

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  • The AB5 toxins are six-component protein complexes secreted by certain pathogenic bacteria known to cause human diseases such as cholera, dysentery, and hemolytic–uremic syndrome. One component is known as the A subunit, and the remaining five components are B subunits. All of these toxins share a similar structure and mechanism for entering targeted host cells. The B subunit is responsible for binding to receptors to open up a pathway for the A subunit to enter the cell. The A subunit is then able to use its catalytic machinery to take over the host cell's regular functions. (en)
  • AB5毒素またはAB5トキシン（英: AB5 toxin）は、コレラ、赤痢、溶血性尿毒症症候群などの疾患を引き起こす特定種の病原性細菌によって分泌されるタンパク質複合体であり、6つの構成要素からなる。構成要素の1つはAサブユニット、残りの5つの構成要素はBサブユニットである。これらの毒素は全て共通した構造と標的宿主細胞への進入機構を有する。Bサブユニットは宿主細胞の受容体への結合を担い、Aサブユニットが細胞内へ進入するための経路を開く。その後、Aサブユニットは自身の触媒装置を用いて宿主細胞の正常な機能を乗っ取る。 (ja)
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  • Enterotoxin
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  • IPR008992 (en)
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  • Enterotoxin (en)
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  • 2 (xsd:integer)
dbp:symbol
  • Enterotoxin (en)
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  • The AB5 toxins are six-component protein complexes secreted by certain pathogenic bacteria known to cause human diseases such as cholera, dysentery, and hemolytic–uremic syndrome. One component is known as the A subunit, and the remaining five components are B subunits. All of these toxins share a similar structure and mechanism for entering targeted host cells. The B subunit is responsible for binding to receptors to open up a pathway for the A subunit to enter the cell. The A subunit is then able to use its catalytic machinery to take over the host cell's regular functions. (en)
  • AB5毒素またはAB5トキシン（英: AB5 toxin）は、コレラ、赤痢、溶血性尿毒症症候群などの疾患を引き起こす特定種の病原性細菌によって分泌されるタンパク質複合体であり、6つの構成要素からなる。構成要素の1つはAサブユニット、残りの5つの構成要素はBサブユニットである。これらの毒素は全て共通した構造と標的宿主細胞への進入機構を有する。Bサブユニットは宿主細胞の受容体への結合を担い、Aサブユニットが細胞内へ進入するための経路を開く。その後、Aサブユニットは自身の触媒装置を用いて宿主細胞の正常な機能を乗っ取る。 (ja)
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  • AB5 toxin (en)
  • AB5毒素 (ja)
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