dbo:abstract
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- 4-Methoxyestriol (4-MeO-E3) is an endogenous estrogen metabolite. It is the 4-methyl ether of 4-hydroxyestriol and a metabolite of estriol and 4-hydroxyestriol. 4-Methoxyestriol has very low affinities for the estrogen receptors. Its relative binding affinities (RBAs) for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) are both about 1% of those of estradiol. For comparison, estriol had RBAs of 11% and 35%, respectively. (en)
- 4-甲氧基雌三醇(英語:4-Methoxyestriol,缩写4-ME3)是一种内源性的雌激素雌三醇的代謝產物。4-ME3可看作是4-羟基雌三醇的4-甲基醚。4-甲氧基雌三醇对的亲和力非常低其对和的相对亲和力(RBAs)只有雌二醇的约1%,相比之下,雌三醇对ERα和ERβ两者的RBAs为11%和35%。 (zh)
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dbo:alternativeName
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- 4-MeO-E3; 4-Methoxyestra-1,3,5(10)-triene-3,16α,17β-triol (en)
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- (1R,2R,3aS,3bR,9bS,11aS)-6-Methoxy-11a-methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1H-cyclopenta[a]phenanthrene-1,2,7-triol (en)
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- 3669 (xsd:nonNegativeInteger)
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rdfs:comment
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- 4-Methoxyestriol (4-MeO-E3) is an endogenous estrogen metabolite. It is the 4-methyl ether of 4-hydroxyestriol and a metabolite of estriol and 4-hydroxyestriol. 4-Methoxyestriol has very low affinities for the estrogen receptors. Its relative binding affinities (RBAs) for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ) are both about 1% of those of estradiol. For comparison, estriol had RBAs of 11% and 35%, respectively. (en)
- 4-甲氧基雌三醇(英語:4-Methoxyestriol,缩写4-ME3)是一种内源性的雌激素雌三醇的代謝產物。4-ME3可看作是4-羟基雌三醇的4-甲基醚。4-甲氧基雌三醇对的亲和力非常低其对和的相对亲和力(RBAs)只有雌二醇的约1%,相比之下,雌三醇对ERα和ERβ两者的RBAs为11%和35%。 (zh)
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rdfs:label
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- 4-Methoxyestriol (en)
- 4-甲氧基雌三醇 (zh)
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