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The enzyme 3-chloro-D-alanine dehydrochlorinase (EC 4.5.1.2) catalyzes the reaction 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3 (overall reaction)(1a) 3-chloro-D-alanine = chloride + 2-aminoprop-2-enoate(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)(1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous)

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  • The enzyme 3-chloro-D-alanine dehydrochlorinase (EC 4.5.1.2) catalyzes the reaction 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3 (overall reaction)(1a) 3-chloro-D-alanine = chloride + 2-aminoprop-2-enoate(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)(1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous) This enzyme belongs to the family of lyases, specifically the class of carbon-halide lyases. The systematic name of this enzyme class is 3-chloro-D-alanine chloride-lyase (deaminating; pyruvate-forming). Other names in common use include β-chloro-D-alanine dehydrochlorinase, and 3-chloro-D-alanine chloride-lyase (deaminating). It employs one cofactor, pyridoxal phosphate. (en)
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  • 4.5.1.2
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  • 14221425 (xsd:integer)
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  • 2248 (xsd:nonNegativeInteger)
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  • 1104099146 (xsd:integer)
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  • 78990 (xsd:integer)
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  • 4.500000 (xsd:double)
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  • 19149 (xsd:integer)
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  • 4 (xsd:integer)
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  • The enzyme 3-chloro-D-alanine dehydrochlorinase (EC 4.5.1.2) catalyzes the reaction 3-chloro-D-alanine + H2O = pyruvate + chloride + NH3 (overall reaction)(1a) 3-chloro-D-alanine = chloride + 2-aminoprop-2-enoate(1b) 2-aminoprop-2-enoate = 2-iminopropanoate (spontaneous)(1c) 2-iminopropanoate + H2O = pyruvate + NH3 (spontaneous) (en)
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  • 3-chloro-D-alanine dehydrochlorinase (en)
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  • 3-chloro-(D)-alanine dehydrochlorinase (en)
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