2B or 2-B may refer to: * 2B (band), a Portuguese band * 2B (film), a 2009 science fiction film * 2B lead, a grading of pencil hardness * 2B (Nier: Automata), the video game's main protagonist * 2b Theatre Company, a theatre company in Halifax, Nova Scotia * 2b2t, а Minecraft server with no rules * Aerocondor, IATA airline code 2B * Alpha-2B adrenergic receptor, a type of protein structure * Haute-Corse, French department 2B (northern Corsica) * Second baseman, a fielding position in baseball * Double (baseball), a type of base hit * Stalag II-B, a prisoner of war camp in Germany * Transcription factor II B, a type of protein structure * Type IIb diamond, a classification of natural diamonds * Type IIB string theory, a physical theory about the basic substance of the univers
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