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- Nia DaCosta directed 28 Years Later: The Bone Temple, with Alex Garland returning as screenwriter. Danny Boyle, who directed 28 Days Later and 28 Years Later, served as a producer on the sequel. (en)
- Alfie Williams, Ralph Fiennes, Jack O'Connell, Aaron Taylor-Johnson, and Cillian Murphy play Spike, Dr Ian Kelson, Sir Jimmy Crystal, Jamie, and Jim respectively (en)
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