The 2022 Worldwide Express 250 for Carrier Appreciation was the 18th stock car race of the 2022 NASCAR Camping World Truck Series, the second race of the Round of 10, and the 14th iteration of the event. The race was held on Saturday, August 13, 2022, in Richmond, Virginia at Richmond Raceway, a 0.75 miles (1.21 km) permanent D-shaped racetrack. The race was contested over 250 laps. Chandler Smith, driving for Kyle Busch Motorsports, dominated the majority of the race, leading 176 laps for his fifth career NASCAR Camping World Truck Series win, along with his third of the season. He would also earn a spot in the next round of the playoffs. To fill out the podium, John Hunter Nemechek, driving for Kyle Busch Motorsports, and Ty Majeski, driving for ThorSport Racing, would finish 2nd and 3rd