The 2021 Akron Zips football team represented the University of Akron during the 2021 NCAA Division I FBS football season. The Zips were led by third-year head coach Tom Arth and played their home games at InfoCision Stadium in Akron, Ohio. They competed as members of the East Division of the Mid-American Conference (MAC). Head Coach Tom Arth was fired on November 4, 2021. His overall record at Akron was 3–24.