The 2006 Sharpie 500 was a NASCAR Winston Cup Series race held on August 26, 2006, at Bristol Motor Speedway, in Bristol, Tennessee. Contested over 500 laps on the 0.533 mile (0.857 km) concrete short track, it was the 24th race of the 2006 NASCAR Nextel Cup Series season. Matt Kenseth of Roush Racing won the race.