The 1938 Holy Cross Crusaders football team represented the College of the Holy Cross during the 1938 college football season. The Crusaders were led by sixth-year head coach Eddie Anderson and played their home games at Fitton Field in Worcester, Massachusetts. Holy Cross's sole loss on the year came on a road trip to Carnegie Tech, where a missed extra point by the Crusaders prevented the tie. They finished ninth in the final AP Poll, the best finish in the Crusaders' history.